Protein Info for QEN71_RS21155 in Paraburkholderia sabiae LMG 24235

Annotation: acyl-CoA dehydrogenase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 PF02771: Acyl-CoA_dh_N" amino acids 8 to 128 (121 residues), 45.2 bits, see alignment E=2.2e-15 PF02770: Acyl-CoA_dh_M" amino acids 133 to 233 (101 residues), 74.2 bits, see alignment E=1.5e-24 PF00441: Acyl-CoA_dh_1" amino acids 245 to 393 (149 residues), 126.7 bits, see alignment E=1.8e-40 PF08028: Acyl-CoA_dh_2" amino acids 262 to 368 (107 residues), 48.9 bits, see alignment E=1.6e-16

Best Hits

KEGG orthology group: K00249, acyl-CoA dehydrogenase [EC: 1.3.99.3] (inferred from 95% identity to bph:Bphy_5044)

Predicted SEED Role

"Isovaleryl-CoA dehydrogenase (EC 1.3.8.4)" (EC 1.3.8.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.3

Use Curated BLAST to search for 1.3.8.4 or 1.3.99.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (416 amino acids)

>QEN71_RS21155 acyl-CoA dehydrogenase family protein (Paraburkholderia sabiae LMG 24235)
MNFGYSPKVEDLRRRVRAFMDEHIVPRHRQWLDEVHAGQFPASFMEDLKAKAKAEGLWNL
FLPHLKEDEPGTRLTNLEYAPLAEIMGRISWAPEVFNCNAPDTGNMELLHMFATPAQREQ
WLVPLLDGTIRSAFAMTEPDVASSDATNITTSIRRDGDDYVINGRKWFITNAAHPNCKLF
IVMGKTDPDAETHQQQSMILVAANTPGLKVVRNIPVMNHISPEGHCEVTFTNVRVPATNL
LGEEGSGFALAQARLGPGRIHHCMRSIGAAELALELMIERSQKRKTFGKYLHQHGAVGEW
IAKSRIEIDQARLLVLKTAWLIDEVGAKAARKEISMIKALVPQLHTTVCDRAMQVFGAMG
VSPDTPLADHWTWGRALRYADGPDEVHLQAIARMEIGASKETLGAAAAYLTPPMRD