Protein Info for QEN71_RS19570 in Paraburkholderia sabiae LMG 24235

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01315: Ald_Xan_dh_C
  • amino acids 30 to 139 (110 residues), 96.5 bits, E=1.9e-31
• PF02738: MoCoBD_1
  • amino acids 176 to 413 (238 residues), 247.3 bits, E=1.9e-77
• PF20256: MoCoBD_2
  • amino acids 441 to 700 (260 residues), 205.1 bits, E=2.6e-64

Predicted SEED Role

"Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4)" in subsystem Purine Utilization (EC 1.17.1.4)

MetaCyc Pathways

• purine nucleotides degradation I (plants) (10/12 steps found)
• adenosine nucleotides degradation I (7/8 steps found)
• guanosine nucleotides degradation II (4/4 steps found)
• superpathway of purines degradation in plants (14/18 steps found)
• superpathway of guanosine nucleotides degradation (plants) (5/6 steps found)
• adenosine nucleotides degradation II (4/5 steps found)
• guanosine nucleotides degradation I (3/4 steps found)
• guanosine nucleotides degradation III (3/4 steps found)
• inosine 5'-phosphate degradation (3/4 steps found)
• purine nucleotides degradation II (aerobic) (8/11 steps found)
• ureide biosynthesis (5/7 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• caffeine degradation III (bacteria, via demethylation) (1/7 steps found)
• theophylline degradation (1/9 steps found)
• caffeine degradation IV (bacteria, via demethylation and oxidation) (1/10 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.17.1.4

Use Curated BLAST to search for 1.17.1.4

Protein Sequence (771 amino acids)

>QEN71_RS19570 xanthine dehydrogenase family protein molybdopterin-binding subunit (Paraburkholderia sabiae LMG 24235)
MKIETTLEEQPAQKQVGRALNRLEARSKVTGRAEYIHNLVLPRMLYGKIFRSTVAHGRIV
GIDTSAARELEGVFAVYTGEDVKRVIPEPYFGPAFHDQPILALDKVRYIGEPVAVVLAAD
PHVAEEATHLIMADYEELPAVFNEVEAAQSDILVHDFLRPAGTFPDLKHLAGRKGTNVAL
DFQLRRGDVDAAFASAAHVFEDTFTTQQVMHTPLEPMVSLAEPDLGSGTLTVHTASQSPS
FVRIEIARLLGWDENRVRVKSALLGGGFGAKLYIKLEALVVALALLSRRAVKVSLTMEEQ
FFTITKHATTFRMKTAVNEEGRITARKCQVWWNGGAYADIGPRVTQKSGFTASGPYDIEN
VWIDSYQVYTNLPPAGAFRGFGIPQMVWAYESHADMISRALRIDPLEFRRRNILREGRPH
ATGTPMHDAAIDLVLERVAQRINWTAPFERGTGTLRRGRGIGIGFKALVAPTTSVAMVNI
AGDGSCTVYSSTVDMGQASETAIALMAGDVLGIPAERIKVMRPDTDVTPYDMATLGSRST
FHMGHAVRLAAEDANRKLRELADELGVAPVPAIRAGELLRRKYGMQAGNIVGIGSFIPGY
KSPEHETGQSENITPNWMVGGCGVEVEVDTETGHFRLLRFENVVDCGTPINPKVVDTQIS
GAAIMQLGITLFERMEFDEVGQLRNASFAEYKIPGIHDIPSAIGRETVDSVQHNGPFGAK
GVGESATFGVASAIADAIEDAVGVRLKSLPLTPESVFRALCAARNEPLSEE