Protein Info for QEN71_RS18285 in Paraburkholderia sabiae LMG 24235

Annotation: circularly permuted type 2 ATP-grasp protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 870 PF04174: CP_ATPgrasp_1" amino acids 100 to 401 (302 residues), 300.6 bits, see alignment E=2e-93 PF14403: CP_ATPgrasp_2" amino acids 100 to 483 (384 residues), 446.5 bits, see alignment E=1.2e-137 PF04168: Alpha-E" amino acids 532 to 858 (327 residues), 181.2 bits, see alignment E=6.1e-57

Best Hits

KEGG orthology group: None (inferred from 95% identity to bph:Bphy_4490)

Predicted SEED Role

"Protein containing domains DUF404, DUF407, DUF403"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (870 amino acids)

>QEN71_RS18285 circularly permuted type 2 ATP-grasp protein (Paraburkholderia sabiae LMG 24235)
MAFQSTFPFEAAAGHPDALALLRTLPLLDVREGHWDELRDASGLLREPWRRFFELLGEEG
VAGLEPGRASIAQQVRDNDITYNVYADKGEPRPWSLDLLPFIIDEDEWAHIERGVKQRAK
LLNAIVADVYGAQKLLLQSKLPPALVFGHPGYLRAVKGFEPQGGQFLQVVGVDLARAPNG
EWTVVSHRTEVPSGLGYALENRMIVSNVFADAFREMRVSRLAPTFSTLIATLAEWARATM
RDGNTDSAPHIALLTPGPFAETYFEHAFLARYLGVTLVEGKDLTVRNDMLYLKTLTGLER
VHVVVRRLDDAFCDPVELRADSTIGVPGLLQVMRAGNVIVSNVPGSGFLESPAMHGFLPG
IAQTLLNEPLLLNGVSTWWCGEEAAREHAFANMDEAFLQPTWPARKPDGPPGMAQGAQRL
DGWKSRIERAPDAFTIQQPLPYSCTPRYEDGTLGNRPGVLRAIAVADVNGDWHVLPGGFT
RLAGERQSSVSMQFGGSSVDTWVLSSQPNSTFTLLPSPLEPADLARKHRTVSSRAAENLF
WSGRYGERAENNVRLLRLILGSLESNGADTMFATLAELALQFGLVQPGDIVAGQSLQAFE
RTLVANLHENTGAYSIGQNLASQARASGEIRGRLSNDHWRITLAARNDFRDALHELTPAA
AVSSNASSRGKARYNRVSLMNALEHLATQLAAISGAQGDRMTRDEAWRLMFAGRHIERVW
AMTSILRVVAMQRQLATPAAFDLLLQLFDSTLTYRSLYPGRLEVPALIDLLVIEPTNPRG
LYGVYARLRSKLDDISRAADGARHRPFSDMLPAANTLPSLEQLCTTDGNGLYTELIALCD
RLAMNVTAAANEISARYFSHANTLAAQVSS