Protein Info for QEN71_RS17430 in Paraburkholderia sabiae LMG 24235

Annotation: response regulator transcription factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 PF00072: Response_reg" amino acids 2 to 104 (103 residues), 68.8 bits, see alignment E=4.6e-23 PF00196: GerE" amino acids 128 to 184 (57 residues), 71.9 bits, see alignment E=2.6e-24

Best Hits

KEGG orthology group: K07688, two-component system, NarL family, response regulator, fimbrial Z protein, FimZ (inferred from 93% identity to bph:Bphy_4334)

Predicted SEED Role

"Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (191 amino acids)

>QEN71_RS17430 response regulator transcription factor (Paraburkholderia sabiae LMG 24235)
MIRGAIASILSSDSELRIVGESGDGEEGLRMVLSLNPDLVVLDLDLPNLDGLSMIRRIRA
QDDGIRILVLSAKPDHVMSLHTQQAGANGYVSKGRELTEMLTAARTVLLGFDCFPASAPH
TGKAGGLDVLSPREMEVLQYLARGVSNKEIASRLFLSDKTVSTYKTRLCEKLGLSSLAAL
IEFATLHKLID