Protein Info for QEN71_RS17405 in Paraburkholderia sabiae LMG 24235

Annotation: HlyD family efflux transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF13533: Biotin_lipoyl_2" amino acids 47 to 90 (44 residues), 26.3 bits, see alignment 7.7e-10 PF13437: HlyD_3" amino acids 205 to 316 (112 residues), 55.3 bits, see alignment E=1.5e-18

Best Hits

KEGG orthology group: K01993, HlyD family secretion protein (inferred from 88% identity to bph:Bphy_4329)

Predicted SEED Role

"Predicted membrane fusion protein (MFP) component of efflux pump, membrane anchor protein YbhG"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (324 amino acids)

>QEN71_RS17405 HlyD family efflux transporter periplasmic adaptor subunit (Paraburkholderia sabiae LMG 24235)
MKPFPFFARGARLVTALAVCAVLGACLQHAGNTWQGYVEGEFVYLGSSQSGKLTQLQVAR
GDQVTADAPVFALESVDETAALQQAQQQLAAARAQLADIQTGKRPPEVDVTKAQLAQAIA
NARKATLQLTRDEAQYRVGGIPKGQLDDTRAAADAANAQVRELTHEVQVARLPGRSQQLL
AQSAQVEAAQAAVAQAQWKLDQKRVSAPAKGRIYDTLYRVGEWVQAGSPVVQMLPPQNVK
VRFFVPETVVGSLAPGRALTIHCDGCASDVNAKITYVSSSAEYTPPVIYSNESRAKLVFM
VEAHPSVDDAPRLHPGQPVSVTLQ