Protein Info for QEN71_RS17090 in Paraburkholderia sabiae LMG 24235

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1176 transmembrane" amino acids 29 to 54 (26 residues), see Phobius details amino acids 321 to 341 (21 residues), see Phobius details amino acids 350 to 373 (24 residues), see Phobius details amino acids 394 to 409 (16 residues), see Phobius details PF00512: HisKA" amino acids 529 to 593 (65 residues), 62.8 bits, see alignment 3.7e-21 PF02518: HATPase_c" amino acids 640 to 755 (116 residues), 92.8 bits, see alignment E=3e-30 PF00072: Response_reg" amino acids 909 to 1017 (109 residues), 71.1 bits, see alignment E=1.3e-23

Best Hits

KEGG orthology group: K07677, two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC: 2.7.13.3] (inferred from 88% identity to bph:Bphy_4270)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1176 amino acids)

>QEN71_RS17090 ATP-binding protein (Paraburkholderia sabiae LMG 24235)
MQNLLDRTQESLAEGFATLLRYARRQRRLYLVTIVALLAILVVSASLLSALAIGKYVDYM
RSIRAQDAANFSVAIHRGQSFLRRAELTVSYYESTDQIQRVSAEAEQAARQSGLLVAAGS
GLDTRYQVLVSEATRARWGDSLNENLWRISSAANSTLVTRAAFDAKYRAVIVGLTDDYAV
LMPELSPSTDPHAPSVSPALIGTLRDTLERNLLAQTGSRAPPKGGYVLSGPYSDPLLGAP
AMVAITAYYSGDTPVALIAIIQPLEQFFNVTARSPYEGTLLLVGKRGVVKTQPPIDADTA
QDLMRQAASLPPDTPRYGLDGVLFSVPVADVLSSLVCHLSWGDIIGALRWQLGAIVGVVL
LAALGVILTAKFWGLKLLRRSNEEAMRALESETINHILVAATPVGLCIVRQRDFHILTSN
QLARELLHLGDAPDSLPAHIAAAFKERNAHEAGASRLGKFAEFIVSALPVEPVAADHPDT
QYLQISYGAARYRGEDVLFCALLDVTVRHALGQQIRAAQRETESMMNAQNSFFAAMSHEI
RTPLNALLGNLELLSMTPGLDVHQQRLRAVGAAADGLRHIVNDILDFSKIGAGKMKLLPE
SFKPIDDLENLALSYAPLASGRPLRFYAHLSPSLYRPIRGDRARVVQIVNNLLSNAFKFT
SSGKITLTAHVEPDLHDRPVLTCRVIDSGIGMDSSLVARIFNPFVQAESSTSSRIGGTGL
GLSICARLCELMGGKIGVESVPGLGSAFTVSIPLEPTAQALADASAALPPRQRGGALVLC
QEAASAKVLGEMLEYVGWTASSATSVAAAEAWLRVHRPGFVIVTGEYDLDTVSALRELQP
VPVVWLTRVGQHRPTQRAEGVFEVTEFSHDAIFACIEQLTGGAPPVETPSAATAGDERAV
DPALQGLRVLVAEDNPLNQTLIVEQLTALGCEPVLAGDGREALLLLKQTEADLVLTDIHM
PIMDGYALMEALRQSHPHLPVLAFSAVAAAEQIDEWRRRGFAAYVPKPASLKQVEAALLT
LGLRARPEPADTDIDTARPEPADTAAQEEETEEASNDDVPPKSPAAPMQQPADTAPALDP
ADKARFMQMLRDYLATDLPRLASIVDSKDVKGLREWAHSAAGGFLVAQETGFAAQCCELQ
YLCDGQSEWTAAHAAHAAALHDRLRSAFEIDVASIQ