Protein Info for QEN71_RS15960 in Paraburkholderia sabiae LMG 24235

Annotation: LysR substrate-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 transmembrane" amino acids 226 to 246 (21 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details PF00126: HTH_1" amino acids 7 to 66 (60 residues), 65 bits, see alignment E=4.8e-22 PF03466: LysR_substrate" amino acids 90 to 292 (203 residues), 110.8 bits, see alignment E=6.1e-36

Best Hits

KEGG orthology group: K03566, LysR family transcriptional regulator, glycine cleavage system transcriptional activator (inferred from 52% identity to reh:H16_B1909)

Predicted SEED Role

"Glycine cleavage system transcriptional activator" in subsystem Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (299 amino acids)

>QEN71_RS15960 LysR substrate-binding domain-containing protein (Paraburkholderia sabiae LMG 24235)
MRTLPSLNALRAFEVCGRLLSVQLAANELNVTPAAVSRQIKLLEDQLGVLLFERGHRAIA
LTPMGERYLADIVRGFETMRTATINLTEARRRRTLKIRGYTTFSMNWLLPRLSTFHREHP
DIEVSLTTSLQPVDFNTEDVDAAIRLSHAPSSDVGHDRLVPNELVPVCSPEFLRAHPDLT
DATPEALRNVPLLHSLARREDWAKWLDAAGVRGVNPLSGLSYESSILAYFAATQGVGVAM
AQRVLVADQLRDGTLVTPFSFVLDLGAFTYYLIYPREHLSNPEFAAFRNWLLSIGEAGR