Protein Info for QEN71_RS15880 in Paraburkholderia sabiae LMG 24235

Annotation: MurR/RpiR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 transmembrane" amino acids 244 to 262 (19 residues), see Phobius details PF01418: HTH_6" amino acids 5 to 78 (74 residues), 75 bits, see alignment E=5.7e-25 PF01380: SIS" amino acids 128 to 234 (107 residues), 52.8 bits, see alignment E=5.7e-18

Best Hits

Swiss-Prot: 39% identical to HEXR_ECOLI: HTH-type transcriptional regulator HexR (hexR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 95% identity to bph:Bphy_4054)

Predicted SEED Role

"Phosphogluconate repressor HexR, RpiR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (288 amino acids)

>QEN71_RS15880 MurR/RpiR family transcriptional regulator (Paraburkholderia sabiae LMG 24235)
MSAPNLIPHIRSALESLRPAERKVADMVLSDVDFAMRASITELAQRADVSEPSVTRFCRA
VGAHGLRDFKMQLAQSVAGGMPYASTAVARDDDTQTLFDKVGEAAVEGITQARGAIDPVA
VNAALAALTGARRVYFFGVGSGSGLVAQDAALRFLRLDIAASAFTDAHLQRLYAGLLEPG
DVAFAISHSGRSVEVNESMQIAKERGATTIALTNVGSRLAWLVDIPLLLRVASPVDPNTP
GVSRLVHLCVMDALAIGVALRLEPRTLEKMRNAKARLAADVAAEDESQ