Protein Info for QEN71_RS15345 in Paraburkholderia sabiae LMG 24235

Annotation: cytochrome o ubiquinol oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 668 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 59 to 79 (21 residues), see Phobius details amino acids 102 to 126 (25 residues), see Phobius details amino acids 141 to 164 (24 residues), see Phobius details amino acids 189 to 212 (24 residues), see Phobius details amino acids 226 to 253 (28 residues), see Phobius details amino acids 278 to 302 (25 residues), see Phobius details amino acids 314 to 333 (20 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 379 to 402 (24 residues), see Phobius details amino acids 414 to 434 (21 residues), see Phobius details amino acids 454 to 475 (22 residues), see Phobius details amino acids 493 to 517 (25 residues), see Phobius details amino acids 588 to 605 (18 residues), see Phobius details amino acids 608 to 626 (19 residues), see Phobius details TIGR02843: cytochrome o ubiquinol oxidase, subunit I" amino acids 2 to 646 (645 residues), 1170 bits, see alignment E=0 PF00115: COX1" amino acids 56 to 503 (448 residues), 510 bits, see alignment E=2.7e-157

Best Hits

Swiss-Prot: 71% identical to CYOB_ECO57: Cytochrome bo(3) ubiquinol oxidase subunit 1 (cyoB) from Escherichia coli O157:H7

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 98% identity to bph:Bphy_3969)

MetaCyc: 71% identical to cytochrome bo3 subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (668 amino acids)

>QEN71_RS15345 cytochrome o ubiquinol oxidase subunit I (Paraburkholderia sabiae LMG 24235)
MFGKLTLADIPYHEPIIVVAGAGMILGALAVLGAITYFGKWRYLWTEWLTSVDHKKLGVM
YIVVAMIMLLRGFADAIMMRTQLALAYHAPGYLPPHHYDQIFTAHGVIMIFFMAMAFMVG
LMNLVVPLQIGARDVAFPFLNSLSFWMTAISAILINISLLIGEFAQTGWLAYPPLSELQF
SPGVGVDYYLWSLQLSGIGTLLTGVNFFVTIIKMRAPGMTLMKMPVFTWTALCTNVLIMA
AFPILTVTLALLGLDRYLGMHFFTNEAGGNAMLYLNLIWAWGHPEVYILILPAFGIFSEV
ISTFSRKPLFGYKTMVYATCAIMVLSFLVWLHHFFTMGSGADVNAFFGIATMIIAVPTGV
KVFNWLFTMYKGRIEFTTPVLWTIGFMVTFTIGGMTGVMMAIPGADFVLHNSLFLIAHFH
NVIIGGVLFGYLAGMNYWFPKAFGFKLNEKLGKAAFWFWQIGFWVAFTPLYVLGFMGMTR
RLNHYDNPAWHPWLLVAEFGAVLVAIGIGCQLLQLVVSIRDRNKPENRDLTGDPWNGRTL
EWATTSPPQIYNFATLPVVHELDAFHDMKARGNVETPVYRDIHMPSNTSAGFFIGVFSLA
LGFALTWHIWWLAIAAFIGAIGTWIARSFDNDIDYYIPADTVQLIEERNGAGSGATIAKQ
LPEAEEIA