Protein Info for QEN71_RS14530 in Paraburkholderia sabiae LMG 24235

Annotation: HlyD family efflux transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 transmembrane" amino acids 33 to 53 (21 residues), see Phobius details PF00529: CusB_dom_1" amino acids 44 to 438 (395 residues), 26.6 bits, see alignment E=9.2e-10 PF13533: Biotin_lipoyl_2" amino acids 73 to 120 (48 residues), 37.4 bits, see alignment 3.5e-13 PF13437: HlyD_3" amino acids 314 to 430 (117 residues), 45.8 bits, see alignment E=1.8e-15

Best Hits

KEGG orthology group: K02022, (no description) (inferred from 97% identity to bph:Bphy_3836)

Predicted SEED Role

"HlyD family secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (457 amino acids)

>QEN71_RS14530 HlyD family efflux transporter periplasmic adaptor subunit (Paraburkholderia sabiae LMG 24235)
MKRDNHPKPLYKALEDHSAEGVAILAAEPVRIAQALVLAMVGLVVAGLLWSFFGRADVIV
TAQGTLAPESDVRRIYAPIDGELTDLYIAEGQPVSKGDVLARLNARGAIQAATDALQAQL
KLEDAEREWKEFPQKKELMERKAAALKDQLEVEERLHENRISEGTTKLAEGQKAQLEEAR
STLDNARRARDAARQEADKYSRLFAQPGGGGVAELQVDAKRNTYMEAENAYRVAQSRLAE
LDFKLSHEYAEANAQLETSGQQATTLQLQYDDLIRDITSTEEKLRLQLQTARLVADAAAR
IRFENIDKDNFLLILAPTSGVITDVTSTQTGDKIQANAPLGGIAPKDARPVLKIEIAERD
RAFLHEGMTVKLKFNAFPYQRYGLINGTLAYISPATKPSAQDKQPVYEGRVQLDKNYYQV
AENRYPLRYGMTASAEIVVRERRLIDLGLDPFRQLAG