Protein Info for QEN71_RS14520 in Paraburkholderia sabiae LMG 24235

Annotation: peptidase domain-containing ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1018 transmembrane" amino acids 127 to 148 (22 residues), see Phobius details amino acids 459 to 481 (23 residues), see Phobius details amino acids 495 to 520 (26 residues), see Phobius details amino acids 570 to 594 (25 residues), see Phobius details amino acids 600 to 618 (19 residues), see Phobius details amino acids 678 to 702 (25 residues), see Phobius details amino acids 715 to 740 (26 residues), see Phobius details PF00027: cNMP_binding" amino acids 38 to 122 (85 residues), 50.3 bits, see alignment E=4.8e-17 amino acids 169 to 256 (88 residues), 65.2 bits, see alignment E=1.1e-21 PF03412: Peptidase_C39" amino acids 307 to 434 (128 residues), 136.4 bits, see alignment E=1.4e-43 PF12385: Peptidase_C70" amino acids 310 to 420 (111 residues), 20.4 bits, see alignment E=1e-07 PF00664: ABC_membrane" amino acids 463 to 729 (267 residues), 157.3 bits, see alignment E=1.7e-49 PF00005: ABC_tran" amino acids 796 to 945 (150 residues), 115 bits, see alignment E=1e-36

Best Hits

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 98% identity to bph:Bphy_3834)

Predicted SEED Role

"ABC-type bacteriocin/lantibiotic exporter, contains an N-terminal double-glycine peptidase domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1018 amino acids)

>QEN71_RS14520 peptidase domain-containing ABC transporter (Paraburkholderia sabiae LMG 24235)
MDAPQTTPTTADFLSTVEILSPFTREELERIAEHVQSRFYSFGETVCNVGDAADGLYVIK
TGSVRIFTEEHGKEISMGVRKTSEVFADIAMLRPYVHESSVRSSGKTELLFIPRAAIEPI
IAGNQAALAFVASYVAINSAGGFVAQLFDLRGKLNKQELEEYVRSVGVKRVAAGKEILKQ
DARDDRRLYVVRQGEVRIVRQEDGNDYTLATLREGEIFGEKACLMRQEQAASAIATTDTR
LLVIPERTVHFILERNPKLREVLDERIKYADRELDRQKRIEQRRKLPLRLDLHTKPELGE
RVIRRFGLVEQAEEMDCGAACLAMICKHYGIPMTLGKLRELANVTTQGATLDSLARAGES
LGFSARGVQCTFDSLRGFDLPFIVHWEGYHYIIVYGVSKDHVWLADPALGFRKLSLEDFE
RGWSGTCLLFAPGPNLVQLSASRSPWLRFIGYLTPYKKILLHLFLATFVIQVLGVIPPLI
IQNILDGVIVHQNISLLHLLILGLIISNVFSQLMSMIRAYLSNFMVRNMDFAMMSQFFRH
TMSLPFSFFAKRKTGDIFARFQENQTIRAFLTESTVTTALNLLMVFIYFAIMFFYNAKMT
FVLIAFVIPIMALTLVATPKIKNYARETFAAATDSKSFLMEALSGVETVKGMGIERPVRL
RWEKKYAKALEVQYRAHAFNIFIGFISQLLNAATTIAILWVGANLVLAREMTIGQLIAFN
AFMGSVLSPLMGLVGLWSMLNDAGVAMERLGDVLDIEPEQKPEDLPSRVMLPDLQGEISL
NGVYFRYGDNDSAYVLENISFEIKPGELIAIVGRSGSGKTTLAKLLVGFYAPSDGKMTVD
GYDMNVIDKAFYRAQIGYVMQTNLLFSGTIAENIASGDDTPDRRRIEEVAKMADAHAFIA
KLPLGYEQIVGERGIGLSGGQIQRLCIARALYHDPRLLVFDEATSALDTQSESNILSNMH
DILKGRTAVIIAHRLSTIMRADKILVLYEGAIVEQGRHEELVNRKGMYYQLVQKQLSA