Protein Info for QEN71_RS14395 in Paraburkholderia sabiae LMG 24235
Annotation: amine dehydrogenase large subunit
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K15229, methylamine dehydrogenase heavy chain [EC: 1.4.98.1] (inferred from 95% identity to bph:Bphy_3809)Predicted SEED Role
"Methylamine dehydrogenase heavy chain precursor (EC 1.4.99.3)" in subsystem Respiratory dehydrogenases 1 (EC 1.4.99.3)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.4.98.1, 1.4.99.3
Use Curated BLAST to search for 1.4.98.1 or 1.4.99.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (385 amino acids)
>QEN71_RS14395 amine dehydrogenase large subunit (Paraburkholderia sabiae LMG 24235) MRIRRRTASIAATLSFAAACIGSAHAIEKPEELTVQKLPAWHPHEVFVVDISMPSMTDAR IYMYDADAKKLLGQIDAGFAPGFAISPDHKTSYVSTTYFARGSHGTRTDVVELTDNSTLD HTGEIVIPPKHGQHVPSPYNTTFSADGKRLYVTNITPAASVTVIDVASKKVLSEVDMAAC VLAYPSGNDRFTGLCESGKALTVTLDANGKETKRVMSDAFIDVDKDPAYINASPYQGGYL FTTFHGMVRSADFRGDKPVFGKAWSLLTDAERAEGWRPGGMQQTAVQAKLHRYYVAMHKG EDGSHKDPGTEIWVYDLQTKKRIARWDLSQQKIDAVASIQVSEDDKPLFYGITGTSDLVV MDARTGKLQNVEKQVGNTSSLLVNP