Protein Info for QEN71_RS13615 in Paraburkholderia sabiae LMG 24235

Annotation: bifunctional diguanylate cyclase/phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 780 transmembrane" amino acids 29 to 49 (21 residues), see Phobius details amino acids 58 to 75 (18 residues), see Phobius details amino acids 83 to 104 (22 residues), see Phobius details amino acids 110 to 129 (20 residues), see Phobius details amino acids 134 to 152 (19 residues), see Phobius details amino acids 164 to 184 (21 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 195 to 352 (158 residues), 126.7 bits, see alignment E=3.8e-41 PF00990: GGDEF" amino acids 199 to 349 (151 residues), 129.9 bits, see alignment E=7.8e-42 PF00563: EAL" amino acids 386 to 605 (220 residues), 133.7 bits, see alignment E=7.3e-43

Best Hits

KEGG orthology group: None (inferred from 95% identity to bph:Bphy_3700)

Predicted SEED Role

"Sensory box/GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (780 amino acids)

>QEN71_RS13615 bifunctional diguanylate cyclase/phosphodiesterase (Paraburkholderia sabiae LMG 24235)
MLFSPTEQTSDAGFRSRFHRRSLEHQRPLSTVTMAFTVVAFIIFVGARSLVAGPAVPLVW
RLACALVLALLVAAIPRTRSISVFGSIGVAYTLVLLAGLALNVAGLDEPLLWALPAIVVI
SVCAAPLWLTPAHFCIGTALFYAAGTPFLLSLPHPHGDVSVVCWMWVLIAVPTAAVFHFG
FYWFRRNHFLLEDRLARLAATDPLTGLQNRRAFLEQAALRLSSLDDGAKVSAIFLDIDYF
KSLNDQFGHAVGDQALSDVARALKELTSAGDIVSRIGGEEFALLHDAALRPAAQLAETLR
AAIGRIARPDGQLSASFGVAEYRPGESVMALLDRADEALLRAKYSGRNRVCAERAKLVDP
VRLTWTHDPADGAAAEPIRQQWDDFWLTSHFQPLYSLSHQKQVGFEALLRGEREDGAQVP
PAVLFSPKPFSDQGELDRVSHALHLGNARRLIPDDAWVFLNILPSTFVADGYPNQLAQIA
RSAGIPCGRVVLELLESHGGSVDDLSRAAGQYRDHGFLIAVDDFGAGHSNLDRLLRIRPD
LVKLDGELIRAKSPGADQPILPKLVSLLHQAGMLVVVEGVETTEQLILAVESNVDFAQGF
LLGRPSPSITPPDAVHRRIDHAFDVIAEGRAHQHALFESEVQPYRQALDTGVDAWLKGTP
LNDAFYDLAQLELCISCFALDDTGRQIGLELPGKASAIDGGSLHPVANPRDARWDHRPYF
RNAVLKPGVPITSSPYLSLASGRPCIAVTVALQSDAGRCVVGAELDWSLQRLPWPTAEHW