Protein Info for QEN71_RS13595 in Paraburkholderia sabiae LMG 24235

Annotation: methyltransferase regulatory domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 527 PF13489: Methyltransf_23" amino acids 44 to 152 (109 residues), 31.9 bits, see alignment E=4.1e-11 PF13847: Methyltransf_31" amino acids 47 to 148 (102 residues), 51.7 bits, see alignment E=3.3e-17 PF02390: Methyltransf_4" amino acids 50 to 107 (58 residues), 28.5 bits, see alignment 3.9e-10 PF13649: Methyltransf_25" amino acids 51 to 148 (98 residues), 57.8 bits, see alignment E=6.1e-19 PF08241: Methyltransf_11" amino acids 52 to 150 (99 residues), 40.9 bits, see alignment E=1.1e-13 PF08242: Methyltransf_12" amino acids 52 to 149 (98 residues), 51.2 bits, see alignment E=7.1e-17 PF10119: MethyTransf_Reg" amino acids 224 to 306 (83 residues), 80.2 bits, see alignment E=6.4e-26 PF21782: PKMT_2nd" amino acids 450 to 525 (76 residues), 47.9 bits, see alignment E=6.1e-16

Best Hits

KEGG orthology group: None (inferred from 43% identity to vap:Vapar_1624)

Predicted SEED Role

"Methyltransferase (EC 2.1.1.-)" (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (527 amino acids)

>QEN71_RS13595 methyltransferase regulatory domain-containing protein (Paraburkholderia sabiae LMG 24235)
MDANKQTNEIQQNYDDYPYYSFPYEQSAPEHLAAVAHVFGLTAPDTRKARVLELGCAAGG
NLIPFAVRNPDARAIGIDLSGVQVQEGRKRVKRLKLNNIELRQQDLMTLGEVDGKFDYIV
CHGVYSWVPPDVQQAILRVCRENLSADGIAYIGYKTYPGWKSREIVRDAMLLRARELKGG
RERLAYGRGMIDFLRQHASKDSVLARAVERDHALIGNGDTGMSAYVAHDYLAPTNAPCYL
QDFVNAAGENGLAYLGDANLPSMFAFNYGDDIGRLLMEECGHSQVAIEQYLDFVSDRSFR
TSLLVHTARADGIAYQVGHERLRALQVAASLTCASGDVHLDDSPQPFTADNGSTIVFNDA
VAKAAAVVLDDAWPFTMSFDALKRDVQALLSAAMTPDETVFDARLDLFINALVVRGFGRF
RVDPVTRRAGNPNLHAALRAYPAQLPEGQLAHTVNPWHQPVQLDAAAQYLLPYIDGSRTR
KQLLGMLSKAVHDGAVTVEQSTSEGAEGTQRAVLADKLEQVLKLLCA