Protein Info for QEN71_RS12835 in Paraburkholderia sabiae LMG 24235

Annotation: ShlB/FhaC/HecB family hemolysin secretion/activation protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 576 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF08479: POTRA_2" amino acids 92 to 148 (57 residues), 30.8 bits, see alignment 2e-11 PF03865: ShlB" amino acids 211 to 539 (329 residues), 111.6 bits, see alignment E=5.8e-36

Best Hits

KEGG orthology group: None (inferred from 88% identity to bph:Bphy_5860)

Predicted SEED Role

"Hemolysin activation/secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (576 amino acids)

>QEN71_RS12835 ShlB/FhaC/HecB family hemolysin secretion/activation protein (Paraburkholderia sabiae LMG 24235)
MVATSAAAALHGTPAAAQAWRDVAPQPAPQPPRSAPSKPQAQTQGNASQVAVDRLIGLVF
EPAGASTAQQQQQPQQAQRVVANALPVLDADFLQSFAADLDKPLTFGRLAEIRQAVIERY
RHAGKPLVDVYVPEQDISSGVVHIDVAEFKLGRVRANGNRYFSSTLLEREMPLVSGDPIL
QTQVSRGLAVLNANPYRRVDAIFAPGEATNTTDVVLQTDDRLPLRANVGYDNQGVPSLGR
DRFFAGLGYGNLFGLDQQIAYQFTASNDFFSGNPDIEGRTNRARFMAHAFSYVAPLPWLD
SIELFGVYAQSTPRLPNTYGQTGISAQFSARYDWRLPSTGDWTQLIQFGYDFKRSNNDLE
FGGFQVFNSNTHIHQFVAVYDISQQKDTGTAHAAATFVASPGGLDGDNSDAAFNTARQGA
TSRYTYLQLTGSDAFALGKGFTLAANGTFQWTPDTLLPSEEIGLGGESSVRGYDPYVVLG
DRGWYAQTELRTPAFALGTNDVLVQPFAFFDAGRVWTRIDQPAEYNPGMLASVGAGVRFR
WSRFVDFRCTYAAPLRAATPDGSKAPMVMLYLTIGT