Protein Info for QEN71_RS11780 in Paraburkholderia sabiae LMG 24235

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00496: SBP_bac_5" amino acids 77 to 457 (381 residues), 336 bits, see alignment E=1.5e-104

Best Hits

Swiss-Prot: 46% identical to HBPA_HAEIN: Heme-binding protein A (hbpA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 81% identity to bgd:bgla_2g06830)

Predicted SEED Role

"Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) or Bacterial Chemotaxis (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (539 amino acids)

>QEN71_RS11780 ABC transporter substrate-binding protein (Paraburkholderia sabiae LMG 24235)
MTSARFPLACFFVALGIAVASLTSVAHAAPSGTLVFCSEGSPAGFDPGQHTTSTDFDAST
NAVYNELVQFKRGTLDLEPALATSWDVSADQRTVTFHLRRGVKFQTTAYFKPTRDFNADD
VLFTFNRMLHTDDPFRKAYPVSFPYFSDLGFDKNIDSIDKTDDYTVRFHLKEPDVIFVRN
IAMNFASILSAEYASKLSETHREADINQYPVGTGPFTFRSYQKDALIRYDANPDYWRPAD
VGLAHLVFAITPDPAARIQKLASGECQVSVFPRPADLDVVKRNPSLTLVSGVGFNVGFVA
YNTQHKPLDQIAVRRALDMAIDKPAIIQAVFSGNATVATNPMPPAQWSYDKALKDAPFDP
SKAKALLAQAGFPNGFDLTLWAMPVQRPYNPNAQLMAQLIQQDWAKIGVHAKIVSYEWGE
YNRRAKQGGEHDAILYGWSGDNGDPDNWLGTLLGCDAVHGSNVSKWCDPGFNGLIEKARA
TSDVQERTRLYEQAQVIFKQQVPYTPVAHSIVSLPESKRVKGLVFSPLGSHRFDGVTLN