Protein Info for QEN71_RS11530 in Paraburkholderia sabiae LMG 24235

Annotation: gluconate:H+ symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 31 to 48 (18 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 104 to 133 (30 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 188 to 210 (23 residues), see Phobius details amino acids 241 to 261 (21 residues), see Phobius details amino acids 281 to 298 (18 residues), see Phobius details amino acids 318 to 336 (19 residues), see Phobius details amino acids 357 to 385 (29 residues), see Phobius details amino acids 396 to 415 (20 residues), see Phobius details amino acids 436 to 458 (23 residues), see Phobius details TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 8 to 458 (451 residues), 394.8 bits, see alignment E=2.8e-122 PF02447: GntP_permease" amino acids 9 to 456 (448 residues), 411.6 bits, see alignment E=3.7e-127 PF03600: CitMHS" amino acids 21 to 401 (381 residues), 44.7 bits, see alignment E=1e-15

Best Hits

KEGG orthology group: K03299, gluconate:H+ symporter, GntP family (inferred from 88% identity to ctt:CtCNB1_4692)

Predicted SEED Role

"Gluconate transporter family protein" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (461 amino acids)

>QEN71_RS11530 gluconate:H+ symporter (Paraburkholderia sabiae LMG 24235)
MTPLDIDLLLTALVSVLVLVALIVSRIKMHPLLALLVVSIGVGFATGMEPQSIVKHLING
AGKTLGAVGIVIALGAMLGKILADAGITEQIAEAILSRASDRMIPWAMTLVAFVVGIPMF
FEVGLVVLLPLIFSVARKLESHARFNGSAYVYVGVPVISALAAMHGMVPPHPGPLTAIAT
LKTSVGPTMLYGFLAAVPAMILGGPLYGAFISPRMSTKPDQALLDQFTLTENADVGQRPG
VGLGVLAALLPAILMLVHAVAEMVLTKGTPAMHVASFLGDPLIAMLLGVLFAAAALVLAR
RGDAGKLRDALSRSLKPIASIIMIIAGGGAFQQMLTSAKVGDAIVHLTQQFAFPPLILGW
LIAMLLSVSTGSATVGIVGAAGLLAPLAGADPSLNLPLLALSIGCGSLFFNYANHAGFWM
VKESFGMTMSDATKTISVVQSIVAVVGLVMALVFNAVVHLH