Protein Info for QEN71_RS11020 in Paraburkholderia sabiae LMG 24235

Annotation: aromatic ring-hydroxylating dioxygenase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 PF00355: Rieske" amino acids 44 to 127 (84 residues), 66.7 bits, see alignment E=1.4e-22 PF00848: Ring_hydroxyl_A" amino acids 186 to 414 (229 residues), 119.6 bits, see alignment E=1.8e-38

Best Hits

KEGG orthology group: K00479, Rieske 2Fe-2S family protein (inferred from 90% identity to bph:Bphy_6857)

Predicted SEED Role

"Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit" in subsystem Phenylpropanoid compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (418 amino acids)

>QEN71_RS11020 aromatic ring-hydroxylating dioxygenase subunit alpha (Paraburkholderia sabiae LMG 24235)
MSEVQIKTHGELIRSRQSGHGMPGELFGRQDVFETDVDVFFHKHWILVGVTADVPEPGDV
SVVDIGKASVIIVRDDDENVRTYRNVCRHRGARLKEAGKSTVGMLVCPYHQWTYDLDGSL
RHASHMGKDFDPTCRSLKPVHTKIVGTHIFVCLAEQPPEDIVKLEETMLPRFAPFDLQNT
KIAFEQEIVEHGNWKLVIENNRECYHCAATHPELTASFLPEDFGFCPDNLSDESLRALEE
YKERNAACQVSWERDGFVCGTVERLDEDAVTQFRTQQLVIAGNGESQTLSTKVASTKLLG
NLERRDLGDTHLWTHNSWTHVMSDHAVISYIIPLAPDRTLVRSKWLVHADAVEGVDYQVS
DLTEVWIATNTQDKHLVEITHEGTQDPAYSPGVFSPFTETYVDQFSRWYAARLSAHGV