Protein Info for QEN71_RS10555 in Paraburkholderia sabiae LMG 24235

Annotation: glycogen synthase GlgA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 4 to 489 (486 residues), 513.7 bits, see alignment E=2.3e-158 PF08323: Glyco_transf_5" amino acids 4 to 242 (239 residues), 219.6 bits, see alignment E=1.3e-68 PF13579: Glyco_trans_4_4" amino acids 19 to 229 (211 residues), 35.7 bits, see alignment E=2.7e-12 PF13439: Glyco_transf_4" amino acids 19 to 230 (212 residues), 30.9 bits, see alignment E=6.8e-11 PF00534: Glycos_transf_1" amino acids 300 to 454 (155 residues), 50.3 bits, see alignment E=5.1e-17 PF13692: Glyco_trans_1_4" amino acids 301 to 454 (154 residues), 39.7 bits, see alignment E=1.5e-13

Best Hits

Swiss-Prot: 53% identical to GLGA_RALSO: Glycogen synthase (glgA) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 89% identity to bph:Bphy_5336)

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.21

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (540 amino acids)

>QEN71_RS10555 glycogen synthase GlgA (Paraburkholderia sabiae LMG 24235)
MTLNVLLVASEAMPLAKSGGLGDMVSAYAAALRDAGVDSTILLPAYPSALERAVGVTPIC
RISGLPGGDARLLRAHMPDTGVPVLLLQMDHLFKRDNLYQDEQGRDYLDNAIRFASLSAA
ATRIARGVRGVQKPDIVHAHDWHTGLTPLLMKVAGVAAKSVFTVHNLAFQGNYPLALGSW
MGVPPELLAPALTDARSIEFYGALSMMKAGIVHAHQVVTVSENYAREILTPHFGHLMEGV
LQASANKLSGITNGIDIDTWNPATDPLIARAYSADDVRGKQTCKRELQQTFGLTVDPFAP
VIAIGSRLTSQKLADVVAEALPVMLARHPRLQVAILGKGDAYLETAMRDLAASWPQRVGV
HIGYDEQRAHMLHAGADLLLHASRFEPCGLTQLYALRYGTIPVASRVGGLRDTIVDYTPE
RSPELGRPEDGATGFLFDGETAEDIASAVQRALDAFMRPSSWHSLQRNAMQCDFSWRKPV
QAYLKLYSALTDARPTQPRVDVERVAANSAQRRANATGTASAHVAWDSAAASQETVARSA