Protein Info for QEN71_RS10155 in Paraburkholderia sabiae LMG 24235

Annotation: lactate permease LctP family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 575 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 40 to 59 (20 residues), see Phobius details amino acids 65 to 93 (29 residues), see Phobius details amino acids 116 to 149 (34 residues), see Phobius details amino acids 160 to 183 (24 residues), see Phobius details amino acids 189 to 212 (24 residues), see Phobius details amino acids 224 to 240 (17 residues), see Phobius details amino acids 252 to 269 (18 residues), see Phobius details amino acids 323 to 342 (20 residues), see Phobius details amino acids 391 to 410 (20 residues), see Phobius details amino acids 431 to 449 (19 residues), see Phobius details amino acids 455 to 479 (25 residues), see Phobius details amino acids 551 to 570 (20 residues), see Phobius details TIGR00795: transporter, lactate permease (LctP) family" amino acids 6 to 567 (562 residues), 708.8 bits, see alignment E=2.4e-217 PF02652: Lactate_perm" amino acids 16 to 565 (550 residues), 674.1 bits, see alignment E=7.6e-207

Best Hits

KEGG orthology group: K03303, lactate transporter, LctP family (inferred from 94% identity to bph:Bphy_5375)

Predicted SEED Role

"L-lactate permease" in subsystem Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (575 amino acids)

>QEN71_RS10155 lactate permease LctP family transporter (Paraburkholderia sabiae LMG 24235)
MHPWYQTYLPLGSLWLSALAASIPIIFFFVALAALRLKGHVAAAGTLILSLAVAIFAYDM
PAPQAFAAAGFGFAYGLWPIAWIIITAVFLYKLVVKTGQFDIIRASVLALTDDQRLQLLL
IGFSFGAFLEGAAGFGAPVAITAALLVGLGFDPLKAAGMCLIANTAPVAFGAMGIPIIVA
GQVTGIDPFLIGATAGRQLPLLSLAVPFWLVFMMDGKRGIKETWPAALVAGGSFAVTQYF
TSNHIGPELPDITSALVSLVALASFLKVWQPRRAHDTARGTGSSTMSGGAAALSGVGGFG
GFGGDGSIGTSRRASPYTLTQTIRAWAPFGILTAVVTVWSLQSFKALFGAKGALAWSIIK
FKVPALDQLVMKTAPIVATPKAYEAVLKIDLLSAVGTAILLTALISMVLLRVKPRDAITT
FVETLKELRRPVLSIGLVLSFAFVANYSGMSSTLALLLAGTGAAFPFFSPILGWLGVFLT
GSDTSSNALFCSLQHTTAHQIGVSDTLLVAANTTGGVTGKMISPQSIAVACAATGLVGRE
SELFRFTVRHSLLFAVIVGLITLLQAYVLPGMLPG