Protein Info for QEN71_RS09710 in Paraburkholderia sabiae LMG 24235

Annotation: cytochrome P450

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 399 PF00067: p450" amino acids 78 to 369 (292 residues), 105.1 bits, see alignment E=2e-34

Best Hits

Swiss-Prot: 54% identical to C1331_XYLFA: Putative cytochrome P450 133B1 (cyp133B1) from Xylella fastidiosa (strain 9a5c)

KEGG orthology group: None (inferred from 91% identity to bph:Bphy_5447)

MetaCyc: 38% identical to pimeloyl-[acp] synthase (Bacillus subtilis subtilis 168)
RXN-13834 [EC: 1.14.14.46]

Predicted SEED Role

"putative cytochrome P450 hydroxylase" in subsystem Nitric oxide synthase

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.14.46

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (399 amino acids)

>QEN71_RS09710 cytochrome P450 (Paraburkholderia sabiae LMG 24235)
MKFTDLSSPAYFDDPYPFYEGIRSAGAFVPLAPSILLTGRHAVIDALLPDRRMGKTYMPS
VVARYGETAREQPVFQALERTFLMMNPPAHTRLRALLMKAFNVRQIETLRTIAEETTDSL
IDAMQGKPEVDLVSEFAMPLPLQIICRLLDVPVEEGERFGDAASLLVSAFDLAPMSPEAL
AKANQAALDLEQYFRAVIAERRAAPGHDIISSLIQAEEGGERLSEDEIVSNVILLFVAGH
ETTSNMLGNALIALHRHPAQLERLKSDPALVSKAVAECARYDTAVQMVVRTAFDDIDVDG
QTLPRGSIVFMLLGSANRDPERFEAADKLDIDREPSGHLLTFGAGIHYCLGARLAMMELE
IALHKLLTRLPQLRLTNLDALQWRRRNNLRGVEKLTAAI