Protein Info for QEN71_RS09505 in Paraburkholderia sabiae LMG 24235
Annotation: FAD-dependent oxidoreductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 42% identical to ANDAA_BURCE: Anthranilate 1,2-dioxygenase system ferredoxin--NAD(+) reductase component (andAa) from Burkholderia cepacia
KEGG orthology group: K00529, ferredoxin--NAD+ reductase [EC: 1.18.1.3] (inferred from 86% identity to bph:Bphy_6979)MetaCyc: 42% identical to anthranilate dioxygenase reductase component (Burkholderia cepacia)
Anthranilate 1,2-dioxygenase (deaminating, decarboxylating). [EC: 1.14.12.1]
Predicted SEED Role
"Ferredoxin reductase" in subsystem Anaerobic respiratory reductases
MetaCyc Pathways
- anthranilate degradation I (aerobic) (1/1 steps found)
- 2-nitrobenzoate degradation II (2/3 steps found)
- superpathway of aromatic compound degradation via 3-oxoadipate (22/35 steps found)
- superpathway of aromatic compound degradation via 2-hydroxypentadienoate (16/42 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.18.1.3
Use Curated BLAST to search for 1.14.12.1 or 1.18.1.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (418 amino acids)
>QEN71_RS09505 FAD-dependent oxidoreductase (Paraburkholderia sabiae LMG 24235) MKRTLVIVGASYAGVQLAASVRELGFDDRIVLLGDEPDAPYQRPPLSKGFLTGSFAEERL PLRSQAFFDEENIEWMPSTRATFIDRERREIELHDGSRIAYDHLALTTGARVRKLDCPGA SLDAVHYLRDLRDAKRLAETARSTKRAVVIGGGYIGLEAAASLRQQGLDVTVVETESRLL ARVASPWISDFMLRAHVQRGVAFELGRKVVALHDAYGVVSVELDNGTRVLCDLVVVGIGV IPNTELAADCGLHVEGGITVDACARTGDPRIVAAGDCASLVPHWAPPGGRVCRIESVQNA NDLAKTAAASILGRCEPYRAVPWFWSDQYDLKLQMAGVNSGFTDFAVRGSVEERKCSLFY FRDNTLIAVDSINRPQDHMLARKLLASGAHVRAEEVRDPAFDLKSLVNGDAHALRGAA