Protein Info for QEN71_RS08315 in Paraburkholderia sabiae LMG 24235

Annotation: dipeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: K01273, membrane dipeptidase [EC: 3.4.13.19] (inferred from 97% identity to bph:Bphy_3302)

Predicted SEED Role

"Microsomal dipeptidase (EC 3.4.13.19)" in subsystem Pyrroloquinoline Quinone biosynthesis (EC 3.4.13.19)

MetaCyc Pathways

leukotriene biosynthesis (2/6 steps found)
gliotoxin biosynthesis (2/9 steps found)
peptido-conjugates in tissue regeneration biosynthesis (6/17 steps found)
arachidonate metabolites biosynthesis (3/74 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.4.13.19

Use Curated BLAST to search for 3.4.13.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (323 amino acids)

>QEN71_RS08315 dipeptidase (Paraburkholderia sabiae LMG 24235)
MSNLHDSSIIIDGLNISKFERSVFEDMRKGGVTAVNCTVSVWEDFQKTIDNIAEMKQQIR
EYSEILTLVRTTDDILRAKKENKTGIIFGFQNSYAFEDNLGYIEVFKELGVNVVQLCYNT
QNLVGTGCYEPDGGLSGYGKEVIQEMNRVGILVDLSHVGAKTSSDAIACSKKPVTYSHCC
PSGLKDHPRNKTDDQLREIADANGFVGVTMFSPFLKKGPDANVDDYLEAIDYVINVIGED
KVGIGTDFTQGYSTEFFDWITHDKGRYRRLTNFGKVVNPEGIRTIGEFPNLTAAMQRAGW
SESRIKKVMGENWMRFFGEVWNV