Protein Info for QEN71_RS06415 in Paraburkholderia sabiae LMG 24235

Annotation: type I methionyl aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00500: methionine aminopeptidase, type I
  • amino acids 3 to 253 (251 residues), 315.9 bits, E=9.6e-99
• PF00557: Peptidase_M24
  • amino acids 13 to 246 (234 residues), 183.2 bits, E=2.8e-58

Best Hits

Swiss-Prot: 62% identical to MAP1_SALTI: Methionine aminopeptidase (map) from Salmonella typhi

KEGG orthology group: K01265, methionyl aminopeptidase [EC: 3.4.11.18] (inferred from 98% identity to bph:Bphy_1339)

MetaCyc: 60% identical to methionine aminopeptidase (Escherichia coli K-12 substr. MG1655)
Methionyl aminopeptidase. [EC: 3.4.11.18]

Predicted SEED Role

"Methionine aminopeptidase (EC 3.4.11.18)" (EC 3.4.11.18)

MetaCyc Pathways

• Arg/N-end rule pathway (eukaryotic) (8/14 steps found)
• Ac/N-end rule pathway (6/21 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.18

Use Curated BLAST to search for 3.4.11.18

Protein Sequence (270 amino acids)

>QEN71_RS06415 type I methionyl aminopeptidase (Paraburkholderia sabiae LMG 24235)
MAITLKNEDDIAQMRIAGRLASEVLDYITPFVKPGVTTGELDRLCHEYMTNVQGTIPAPL
NYQPPGYPPFPKAVCTSVNDVICHGIPGDKALKNGDALNIDVTVIKNGYYGDTSRMFLVG
EGSIMAKRLVQTTYECMWLGIEQVRPGAHLGDIGHAIQKHAEGLGYSVVREYCGHGIGQV
FHDEPQILHYGRPGTGIELQAGMIFTIEPMINAGRRDIRTMPDQWTVKTKDRSLSAQWEH
TILVTPTGYEVLTVSEGTPARPQIVAAATA