Protein Info for QEN71_RS06370 in Paraburkholderia sabiae LMG 24235

Annotation: succinyldiaminopimelate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 TIGR03538: succinyldiaminopimelate transaminase" amino acids 1 to 399 (399 residues), 608.6 bits, see alignment E=2.4e-187 PF00155: Aminotran_1_2" amino acids 32 to 388 (357 residues), 168.6 bits, see alignment E=1.2e-53

Best Hits

KEGG orthology group: K14267, N-succinyldiaminopimelate aminotransferase [EC: 2.6.1.17] (inferred from 96% identity to bph:Bphy_1348)

MetaCyc: 60% identical to N-succinyldiaminopimelate-aminotransferase (Bordetella pertussis)
Succinyldiaminopimelate transaminase. [EC: 2.6.1.17]

Predicted SEED Role

"N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17)" in subsystem Lysine Biosynthesis DAP Pathway (EC 2.6.1.17)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.17

Use Curated BLAST to search for 2.6.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (405 amino acids)

>QEN71_RS06370 succinyldiaminopimelate transaminase (Paraburkholderia sabiae LMG 24235)
MNPLLDSLQPYPFEKLRLLFKDVTPPAHLSHISFGIGEPKHPTPELIRKAVIDSLGGLAA
YPATIGAPALREAIAKWVTTRYNLPPVDPATQVLPVAGSREALFALAQTVIDPKKNAGGE
PAIVLCPNPFYQIYEGAALLAGAQPYFANSDPKRNFACDYSAIPDDIWARTQLLYVCSPG
NPTGAVLTLDDWRELFELSDRHGFVIASDECYSEIYFDEARPPLGGLEAAHKLGRGFERL
VMLSSLSKRSNVPGMRSGFVAGDASILKQFLLYRTYHGAALSTVYQTASIAAWSDEAHVR
ENRAMYVQKFSTVTPMLADVLDVKLPDAAFYLWANVARTGLSDAEFAQRLYADYNVTVLP
GSYLARTAHDTNPGRDFVRLALVAGVDECTEGVQRIVGFCRSLKR