Protein Info for QEN71_RS06060 in Paraburkholderia sabiae LMG 24235

Annotation: ATP-dependent DNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 754 PF13307: Helicase_C_2" amino acids 573 to 734 (162 residues), 145.1 bits, see alignment E=2.2e-46

Best Hits

KEGG orthology group: K03722, ATP-dependent DNA helicase DinG [EC: 3.6.4.12] (inferred from 96% identity to bph:Bphy_1403)

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (754 amino acids)

>QEN71_RS06060 ATP-dependent DNA helicase (Paraburkholderia sabiae LMG 24235)
MNSPLQSSSRPASDDASGAVASVADERATKGATGGGALAASLTHKRSSELADIFAADGLL
ARQIDGYRPRASQIEMARAVAAAMEASGRAMPEPAMFEAQKRPARRLQQSSSAADAQSDA
SPAAESNLEGGENTLIVEAGTGTGKTYAYLVPAMLWGGKVIVSTGTKHLQDQLFQRDIPT
VRDALAVPVSVAMLKGRANYLCHYYLQRTADNGRLPSRQETSYLQDIIRFAKITRTGDKA
ELASVPETAAVWSMVTSTRDNCLGQECPHYKDCFVMQARREAQQADIVVVNHHLFFADIM
LRDTGMAELLPTANTVIFDEAHQLPETATLFFGETLSTTQFLELARDSVAEGLGHARDAV
DWVKLGAALERSARDVRLAFKEDSVRLSIGQLPDDHPLFPALEAVETELDALADALAGQS
ERAESLGALLRRARELQEVLSGWTTPPTETEREAASDAGAAAEKSDPNEKVRWIEVFSHT
VQLHETPLSVAPIFAKQRAGVPRAWVFTSATLSVRGDFTHYAAQMGLNSRRSMTLPSPFD
YGTQGLLYVPRNLPQPSSPMFTDAVFDAALPAIEASGGGVFMLCTTLRAVDRIASKLRDV
IESRGWNMPLLVQGDASRTELLDRFRSYGNAILVGSQSFWEGVDVRGDALSLVVIDKLPF
APPDDPVLSARLDALTKKGLSPFAVHQLPQAVITLKQGAGRLIRSETDRGVLMICDTRLV
DKPYGRRIWQSLPPFKRTRELDVVREFFEENAQA