Protein Info for QEN71_RS05695 in Paraburkholderia sabiae LMG 24235

Annotation: M3 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 704 PF19310: TOP_N" amino acids 49 to 156 (108 residues), 90.1 bits, see alignment E=9.6e-30 PF01432: Peptidase_M3" amino acids 229 to 693 (465 residues), 486.8 bits, see alignment E=9.6e-150

Best Hits

Swiss-Prot: 50% identical to OPDA_SALTY: Oligopeptidase A (prlC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01414, oligopeptidase A [EC: 3.4.24.70] (inferred from 97% identity to bph:Bphy_1476)

MetaCyc: 50% identical to oligopeptidase A (Escherichia coli K-12 substr. MG1655)
Oligopeptidase A. [EC: 3.4.24.70]

Predicted SEED Role

"Oligopeptidase A (EC 3.4.24.70)" in subsystem Protein degradation (EC 3.4.24.70)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (704 amino acids)

>QEN71_RS05695 M3 family metallopeptidase (Paraburkholderia sabiae LMG 24235)
MSTSQSTSDNPLLDFSDLPRFGEIRPEHVTPALDVLLANASAAVERAAEPSTPASWADVV
EPVERATEPLSRAWGVIGHLNAVADTPELRAVYGENLPRVTEFWSSVGQNLALYEKYKAI
AASDDFGSLTGERKKILNNSLRDFRLSGAELPEDQKPRFAELQERQAALSKAFSDHVLDA
TNAYACFAESKDELVGLPEDVIEAAHEAAERESKSGWKFTLHFPSYFPVMQYSENRAMRE
TMYRAYVTRASELGPQYGKGNAEWDNTANVAENLKLREEEAHMLGYRNFAEVSLAPKMAE
SPEQVMAFLEDLATRARPHAEHDWTELREFASGELGLSELQPWDVAFAAERLRQKRYSFS
ENEVKQYFPEDIVLKGLFKVTETLFGVKIRRDEAATWHPDVRFFRVENQDGGLVAQFYLD
LYAREGKRGGAWMDDARSRRKPVNGAVQTPVAYLTCNFSAPVGGKPACFTHDEVITLFHE
FGHGLHHMLTRVDELGVSGINGVEWDAVELPSQFMENFCWEWDVLSDMTQHVDTAKPLPR
DLFDKMLAAKNFQSGLGTLRQIVFSMFDMKLHVDFDTSGAKSANDLAREINERFHVIPQA
AFSRWPNTFSHIFAGGYAAGYYSYKWAEVLSADAYAAFEEAAQAGKGSVLDVATGTRYRK
EILEVGGSRPAMESFKAFRGREPNIDALLRHNGMAPGSTPGAAH