Protein Info for QEN71_RS03055 in Paraburkholderia sabiae LMG 24235

Annotation: acyl-CoA desaturase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00487: FA_desaturase
  • amino acids 17 to 220 (204 residues), 53.8 bits, E=2.5e-18
• PF01610: DDE_Tnp_ISL3
  • amino acids 275 to 397 (123 residues), 40.4 bits, E=2.9e-14

Best Hits

KEGG orthology group: K00507, stearoyl-CoA desaturase (delta-9 desaturase) [EC: 1.14.19.1] (inferred from 97% identity to bph:Bphy_0579)

Predicted SEED Role

"Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1)" (EC 1.14.19.1)

MetaCyc Pathways

• palmitoleate biosynthesis IV (fungi and animals) (2/2 steps found)
• oleate biosynthesis II (animals and fungi) (1/2 steps found)
• sorgoleone biosynthesis (2/8 steps found)

KEGG Metabolic Maps

• Biosynthesis of unsaturated fatty acids

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.19.1

Protein Sequence (398 amino acids)

>QEN71_RS03055 acyl-CoA desaturase (Paraburkholderia sabiae LMG 24235)
MLNSLLDFLAHGALRFSWWQIVLWTLAVTHVTIIGVTVYLHRCQAHRALDLHPIASHFFR
FWLWMSTGMLTGQWAAIHRKHHAKCETEEDPHSPQTRGIWKVLLEGAELYRTEAKNEETM
RKFSHGTPNDWLERNVYTKYPILGVSLMMVIDVALFGIVGLTVWAVQMIWIPFWAAGVVN
GLGHFWGYRNFNSSDASTNLFPWGIIIGGEELHNNHHTYATSAKLSNKWYEFDIGWMYIR
IMSAFRLAKVKKIAPTPRLTTGKLVLDQDTLQAVLANRYEVMASYAKAIKRAYRQELAHL
KEVGAREKYQLMRGARSWFHKEEAGLDEPQRLQLPQIFASSQKLRTYIELRNELAAMWER
SNASREQLLVQLQDWCHRAEQSGIKALQEFAMRLRRYA