Protein Info for QEN71_RS02960 in Paraburkholderia sabiae LMG 24235

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 701 TIGR00484: translation elongation factor G" amino acids 1 to 700 (700 residues), 1200.4 bits, see alignment E=0 TIGR00231: small GTP-binding protein domain" amino acids 9 to 187 (179 residues), 107.2 bits, see alignment E=7.4e-35 PF00009: GTP_EFTU" amino acids 9 to 289 (281 residues), 215.4 bits, see alignment E=1.3e-67 PF03144: GTP_EFTU_D2" amino acids 330 to 397 (68 residues), 71 bits, see alignment E=2.3e-23 PF14492: EFG_III" amino acids 410 to 484 (75 residues), 118.5 bits, see alignment E=2.7e-38 PF03764: EFG_IV" amino acids 485 to 604 (120 residues), 164.7 bits, see alignment E=1.9e-52 PF00679: EFG_C" amino acids 606 to 693 (88 residues), 105.3 bits, see alignment E=3.5e-34

Best Hits

Swiss-Prot: 93% identical to EFG2_BURL3: Elongation factor G 2 (fusA2) from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)

KEGG orthology group: K02355, elongation factor G (inferred from 94% identity to bmv:BMASAVP1_A0548)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (701 amino acids)

>QEN71_RS02960 elongation factor G (Paraburkholderia sabiae LMG 24235)
MPRKTPIERYRNIGISAHIDAGKTTTTERILFYTGVTHKIGEVHDGAATMDWMEQEQERG
ITITSAATTAFWKGMAGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYDSVGGVQ
PQSETVWRQANKYKVPRIAFVNKMDRVGADFFRVQKQIGERLKGVAVPIQIPIGAEEHFQ
GVVDLVKMKAIVWDDESQGIKFTYEEIPDNLKELAHEWREKMVEAAAEASEEMLEKYLTD
HESLTEDEIKAGIRKRTIANEIVPMLCGSAFKNKGVQAMLDAVIDYLPSPVDVPAILGHT
EDDKEAERHPSDDEPFSALAFKIMTDPFVGQLIFFRVYSGVVESGDTVYNPVKEKKERLG
RILQMHANERKEIKEVRAGDIAAAVGLKEATTGDTLCDPNNIIILERMIFPEPVISQAVE
PKTKVDQEKMGIALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEA
TVGKPQVAYRETVRTKVEDVEGKFVKQSGGRGQYGHAVISLEPDPGKGYEFIDAIKGGVI
PREFIPAVDKGIQETLKAGVLAGYPVVDVKVTLTFGSYHDVDSNENAFRMAGSMAFKEAM
RKAKPVLLEPMMAVEVETPEDFMGNVMGDLSGRRGIVQGMEDIAGGGGKLVRAEVPLSEM
FGYSTSLRSLTQGRATYTMEFKQYAETPNNVSEAIINSKSK