Protein Info for QEN71_RS02600 in Paraburkholderia sabiae LMG 24235

Annotation: carbohydrate ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 transmembrane" amino acids 30 to 50 (21 residues), see Phobius details amino acids 84 to 109 (26 residues), see Phobius details amino acids 120 to 143 (24 residues), see Phobius details amino acids 155 to 176 (22 residues), see Phobius details amino acids 197 to 220 (24 residues), see Phobius details amino acids 252 to 273 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 102 to 275 (174 residues), 52 bits, see alignment E=3.8e-18

Best Hits

KEGG orthology group: K10229, sorbitol/mannitol transport system permease protein (inferred from 96% identity to bph:Bphy_0492)

MetaCyc: 68% identical to polyol ABC-type transporter permease component MtlG (Pseudomonas fluorescens)
7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]

Predicted SEED Role

"Various polyols ABC transporter, permease component 2" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.M2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (288 amino acids)

>QEN71_RS02600 carbohydrate ABC transporter permease (Paraburkholderia sabiae LMG 24235)
MSQVAATPVTTNVSKVNSPFAIIRRSIPGILAWIIALLLFFPIFWMTITAFKTEQQAYAS
SLFFTPTLESFREVFARSNYFGFAWNSILISVGVTLLCLILAVPCAYAMAFFPTRRTQKV
LLWMLSTKMMPSVGVLVPIYLLWKNSGLLDTVSGLVIVYTLINLPIAVWMSFTYFAEIPR
DILEAGRIDGAATWQEIVYLLMPMSLPGLASTALLLVILSWNEAFWSINLSSSNAAPLTV
FIASYSSPEGLFWAKLSAASLLAVAPILIVGWVSQKQLVRGLTFGAVK