Protein Info for QEN71_RS02060 in Paraburkholderia sabiae LMG 24235

Annotation: acyl-CoA dehydrogenase C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 595 PF12418: AcylCoA_DH_N" amino acids 3 to 35 (33 residues), 50.5 bits, see alignment (E = 4.8e-17) PF02771: Acyl-CoA_dh_N" amino acids 41 to 159 (119 residues), 37.9 bits, see alignment E=6.3e-13 PF02770: Acyl-CoA_dh_M" amino acids 164 to 273 (110 residues), 55.9 bits, see alignment E=1.2e-18 PF00441: Acyl-CoA_dh_1" amino acids 283 to 451 (169 residues), 71.4 bits, see alignment E=3e-23 PF12806: Acyl-CoA_dh_C" amino acids 470 to 591 (122 residues), 119.2 bits, see alignment E=3.6e-38

Best Hits

KEGG orthology group: K00257, [EC: 1.3.99.-] (inferred from 96% identity to bph:Bphy_0385)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7, 1.3.99.-

Use Curated BLAST to search for 1.3.8.7 or 1.3.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (595 amino acids)

>QEN71_RS02060 acyl-CoA dehydrogenase C-terminal domain-containing protein (Paraburkholderia sabiae LMG 24235)
MGQYAAPLRDMQFVLHELLNVEAEIKQMPKHADLDADTINQVLEEAGKFCSEVLFPLNQS
GDQEGCKYEGDGVVTTPKGFKEAYRQYIEAGWPALGCDPDFGGQGLPAFVNNALYEMMNS
ANQAWTMYPGLSHGAYECLHAHGTPELQQAYLPKLVSGEWTGTMCLTEPHCGTDLGILRT
KAEPNSDGSYSISGTKIFISSGEHDLADNIIHLVLARLPDAPQGTKGISLFVVPKFVPDA
SGAPGERNGVKCGSIEHKMGIHGNATCVINLDNAKGWLVGEPNKGLNAMFVMMNAARLGV
GMQGLGLTEVAYQNSLVYAKERLQMRSLTGPKAPEKAADPIIVHPDVRRMLLTQKAYAEG
ARAFTYWSALHIDKELSHADESVRKEAGDLVALLTPIIKAFLTDNAFEGTNMAMQIYGGH
GFIAEWGMEQYVRDARINMIYEGTNSIQSLDLLGRKVLGDMGAKLKKFGKLVSDFVEEEG
IKPEMQEFVNPLADIGDKVQKLTMEIGMKAMQNPDEVGAAAVPYLRTVGHLVFSYFWARM
ARIALDNQASGDPFYKSKLATARFYFAKLLPETASTIRAARAGSKTLMEIDEALF