Protein Info for QEN71_RS00925 in Paraburkholderia sabiae LMG 24235

Annotation: solute carrier family 23 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 transmembrane" amino acids 32 to 53 (22 residues), see Phobius details amino acids 60 to 77 (18 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 111 to 137 (27 residues), see Phobius details amino acids 144 to 163 (20 residues), see Phobius details amino acids 173 to 191 (19 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details amino acids 239 to 261 (23 residues), see Phobius details amino acids 281 to 307 (27 residues), see Phobius details amino acids 319 to 338 (20 residues), see Phobius details amino acids 350 to 373 (24 residues), see Phobius details amino acids 384 to 401 (18 residues), see Phobius details amino acids 407 to 425 (19 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 26 to 423 (398 residues), 352.2 bits, see alignment E=2.1e-109 PF00860: Xan_ur_permease" amino acids 31 to 399 (369 residues), 302.9 bits, see alignment E=1.4e-94

Best Hits

Swiss-Prot: 71% identical to RUTG_ECOLI: Putative pyrimidine permease RutG (rutG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to bph:Bphy_0138)

MetaCyc: 71% identical to pyrimidine:H+ symporter (Escherichia coli K-12 substr. MG1655)
RXN-5076; TRANS-RXN-132; TRANS-RXN-362

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (435 amino acids)

>QEN71_RS00925 solute carrier family 23 protein (Paraburkholderia sabiae LMG 24235)
MADSYFPRWRVQPKSVEGRVVNTDERLPAPQMFAMGIQHVVAMFGSTVLAPLLMGFDPNL
CIFMSGIGTLLFFVLVGGRVPSYLGSSFAFIGLVIAITGYTGQGPNMNIPVALGGIIACG
VAYVVIGLIVSAIGTAWIETLMPPVVTGSIVAVIGLNLAPIAVKGVSGSAFDSYMALVTV
LCVGAVAVFAHGMLQRLLILVGLLIAYAIYAVVTNGMGMGKPIDFSIVANAPWFGMPHFM
APVFSGQAMALLAPVAVILVAENLGHIKAVSAMTGQNLDGYIGRAFIGDGLATVLSGFAG
GTGVTTYAENIGVMAVTKIYSTLVFVIAALIALVLGFSPKFGAVIATIPGPVLGGVSIVV
FGLIAVTGARIWVVNKVNFSDNRNLIVAAVTLVLGAGDFSLKFGGFALGGIGTATFGAII
LYALLRRKGPQEPAV