Protein Info for Psyr_4742 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Protein of unknown function DUF423

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 126 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 39 to 60 (22 residues), see Phobius details amino acids 67 to 89 (23 residues), see Phobius details amino acids 99 to 120 (22 residues), see Phobius details PF04241: DUF423" amino acids 19 to 105 (87 residues), 98.4 bits, see alignment E=1.1e-32

Best Hits

Swiss-Prot: 49% identical to YWDK_BACSU: UPF0382 membrane protein YwdK (ywdK) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_4742)

Predicted SEED Role

"COG2363"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZM53 at UniProt or InterPro

Protein Sequence (126 amino acids)

>Psyr_4742 Protein of unknown function DUF423 (Pseudomonas syringae pv. syringae B728a ΔmexB)
MLRSFLMLAAFFGFTGVALGAFAAHGLKERLSAEYLAVFHTGVLYQLIHALALLGVAILA
THIPGRLVTWAGFSFAVGILLFSGSLYALTLTGFSKLGIITPFGGLAFLFGWSMLGLAAW
RLGSPP