Protein Info for Psyr_4520 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Excinuclease ABC subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 961 TIGR00630: excinuclease ABC subunit A" amino acids 20 to 941 (922 residues), 1489.8 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 147 to 254 (108 residues), 134.6 bits, see alignment E=4.4e-43 PF17755: UvrA_DNA-bind" amino acids 307 to 415 (109 residues), 115.1 bits, see alignment E=7e-37

Best Hits

Swiss-Prot: 76% identical to UVRA_ECO57: UvrABC system protein A (uvrA) from Escherichia coli O157:H7

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 75% identity to abo:ABO_0427)

MetaCyc: 76% identical to UvrABC excision nuclease subunit A (Escherichia coli K-12 substr. MG1655)
3.1.25.-

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZMS2 at UniProt or InterPro

Protein Sequence (961 amino acids)

>Psyr_4520 Excinuclease ABC subunit A (Pseudomonas syringae pv. syringae B728a ΔmexB)
MARSRILRRLCPPSEAAVDKILIRGARTHNLKNIDLTLPRDKLIVITGLSGSGKSSLAFD
TLYAEGQRRYVESLSAYARQFLSMMEKPDVDTIEGLSPAISIEQKSTSHNPRSTVGTITE
IYDYLRLLYARVGQPRCPDHDIPLEAQTVSQMVDLVLSQPEGSKLMLLAPVIRERKGEHL
SVFEELRAQGFVRARVNGKLCELDELPKLDKQKKHSIDVVVDRFKVRADLQQRLAESFET
ALKLADGIALVAPMDDEPGEEVIFSARFACPICGHAISELEPKLFSFNNPAGACPTCDGL
GVKQFFDIKRLVNAELTLAEGAIRGWDRRNVYYFQMLGSLSKHYGFSLEMPFKQIPADMQ
KILLNGSGSQSVDFRYLNDRGDIVKRAHPFEGIVPNLERRYRETESATVREELAKFLGTQ
PCPDCRGTRLRREARHVWVGEKTLPAVTSLPIGDATHYFETLKLTGRRGEIADKILKEIR
ERLQFLVNVGLDYLTLDRSADTLSGGEAQRIRLASQIGAGLVGVMYILDEPSIGLHQRDN
DRLLGTLKHLRDIGNTVIVVEHDEDAIRLADYVVDIGPGAGVHGGHIVAEGTPDEVMSHP
DSLTGKYLSGRVKIAVPAKRTPRNKKLSLTLKGARGNNLQNVNLDIPIGLLTCVTGVSGS
GKSTLINNTLFPLSATALNGATTLEAATHDSINGLQHLDKVVDIDQSPIGRTPRSNPATY
TGLFTPIRELFAGVPESRSRGYGPGRFSFNVKGGRCEACQGDGLIKVEMHFLPDIYVPCD
VCKSKRYNRETLEVKYKGKNIHEVLEMTIEEAREFFDAVPALARKLQTLMDVGLSYIKLG
QSATTLSGGEAQRVKLSRELSKRDTGKTLYILDEPTTGLHFADIQQLLDVLHRLRDHGNT
VVVIEHNLDVIKTADWLVDLGPEGGSRGGQIIATGTPEQVAEMEQSYTGHYLKPLLTRDK
A