Protein Info for Psyr_4424 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Propeptide, PepSY amd peptidase M4:PepSY-associated TM helix

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 transmembrane" amino acids 15 to 39 (25 residues), see Phobius details amino acids 144 to 164 (21 residues), see Phobius details amino acids 190 to 211 (22 residues), see Phobius details amino acids 374 to 395 (22 residues), see Phobius details amino acids 416 to 442 (27 residues), see Phobius details PF03929: PepSY_TM" amino acids 13 to 397 (385 residues), 256 bits, see alignment E=6.9e-80 PF03413: PepSY" amino acids 286 to 343 (58 residues), 25.6 bits, see alignment 1.3e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_4424)

Predicted SEED Role

"Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZN18 at UniProt or InterPro

Protein Sequence (457 amino acids)

>Psyr_4424 Propeptide, PepSY amd peptidase M4:PepSY-associated TM helix (Pseudomonas syringae pv. syringae B728a ΔmexB)
MSKPDVSFYNLAWRWHFYAGLFVAPFMILLSLTGIIYLFKPQLDNLMYSDLLNVAPAEHR
LTADVLQQRVLSTYPHATVGKYFPPTSTVGSAQFVVSEQGRELNVFIDPYRGDILGTQDA
TKNLQAVARALHGELMIGTLGDRLVELAAGWGVVLVISGLYLWWPRGRSAAGVFWPRLTA
KGRVLWRDLHAVTGFWGALLLLFMLLSGMTWTGLWGKQYAAVWNTFPAAMWTDVPKSDRQ
AGELNNASVQTVPWAMENTPMPVSTGEHAEHMDHMHMSSAPAAPTVSLQKVVDIARARDI
VPGYSITQPKTADGVFTVSVFADDPRDDATLHIDQYTGKVLADVRYVDYSTVSKATELGV
MLHEGKFFGWINQLLILLVCLMVLLSSVSGLVIWWKRRPQRGLGVPPLRHDLPRWKTATV
VMIALGAVFPLVGISMLIVWVLDRIVLSRFAKQATTA