Protein Info for Psyr_4313 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Beta-ketoacyl synthase:Beta-ketoacyl synthase:Phosphopantetheine-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF08659: KR
  • amino acids 267 to 457 (191 residues), 125.6 bits, E=1.1e-39
• PF01370: Epimerase
  • amino acids 270 to 411 (142 residues), 26.6 bits, 2e-09
• PF00106: adh_short
  • amino acids 270 to 436 (167 residues), 40.2 bits, 1.4e-13
• PF00550: PP-binding
  • amino acids 557 to 619 (63 residues), 31.3 bits, see alignment (E = 9.8e-11)
  • amino acids 1401 to 1464 (64 residues), 44 bits, see alignment (E = 1.1e-14)
• PF00109: ketoacyl-synt
  • amino acids 669 to 921 (253 residues), 268.2 bits, E=3.9e-83
  • amino acids 1502 to 1747 (246 residues), 259 bits, E=2.6e-80
• PF02801: Ketoacyl-synt_C
  • amino acids 929 to 1046 (118 residues), 143.2 bits, 1.9e-45
  • amino acids 1756 to 1871 (116 residues), 130.4 bits, 1.7e-41
• PF16197: KAsynt_C_assoc
  • amino acids 1050 to 1150 (101 residues), 37.9 bits, see alignment (E = 1e-12)
  • amino acids 1876 to 1977 (102 residues), 44.5 bits, see alignment (E = 9.7e-15)
• PF21089: PKS_DH_N
  • amino acids 2099 to 2190 (92 residues), 42.2 bits, see alignment (E = 3.3e-14)
• PF14765: PS-DH
  • amino acids 2240 to 2385 (146 residues), 65.4 bits, 2.3e-21

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_4313)

Predicted SEED Role

"Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)" in subsystem Fatty Acid Biosynthesis FASII or mycolic acid synthesis (EC 2.3.1.39)

MetaCyc Pathways

• superpathway of fatty acids biosynthesis (E. coli) (51/53 steps found)
• superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
• superpathway of fatty acid biosynthesis I (E. coli) (15/16 steps found)
• fatty acid biosynthesis initiation (type II) (3/3 steps found)
• superpathway of fatty acid biosynthesis initiation (4/5 steps found)
• fatty acid biosynthesis initiation (mitochondria) (2/4 steps found)
• fatty acid biosynthesis initiation (plant mitochondria) (1/4 steps found)
• mycobactin biosynthesis (3/11 steps found)
• pederin biosynthesis (2/14 steps found)
• bryostatin biosynthesis (2/19 steps found)
• mupirocin biosynthesis (2/26 steps found)
• corallopyronin A biosynthesis (2/30 steps found)

KEGG Metabolic Maps

• Fatty acid biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.39

Use Curated BLAST to search for 2.3.1.39

Sequence Analysis Tools

See Q4ZNC9 at UniProt or InterPro

Protein Sequence (2393 amino acids)

>Psyr_4313 Beta-ketoacyl synthase:Beta-ketoacyl synthase:Phosphopantetheine-binding protein (Pseudomonas syringae pv. syringae B728a ΔmexB)
MNNSNEIANFQRYIIDQLKAGRITKEQAVQALAKTDATGGSMREEQSGPPGSTRYVPVWR
DAPLGRALDVAQAHEQHCVVVVTEHGHERLVDTLKARLDQRLLARMTVVLAPEEAAAKGT
LADQMSGLASAMILDVFLSLKAQVTAILQHGKGRKSSADTLLQVFFLRPDSYAEDKVAHE
SVYVGVEAAISAMLKTLNKEHPSITTQLVALDEASLGQLSQNSLAEEQHSHAAYVRYLKN
VRYVQVFETLSDRSDGASLQSFIKTDASYLIIGGVGGIGLHLADYILRQGQQARVVLTGR
RSEADLQSNTPYLQLVNTYGKSRVSYLTANAASYSDLKSLLIKVVASHHLEGIFHCAGTL
NDSFLVNKTVEQFENTLEAKVSGSLHLIQAANDVSQQTETGFDFILFCSSCAGQLGFVGQ
IDYAAGNGFIDGFSDARNKVGRNGFDRLLSVNWPLWENAGMGVDQQALKELHVEYGLLPL
PVDVALNHVNTLLLAADTHHVLVTYGDPVKIDSQYVNAKPQRNLQTPALSQQTAQAASGK
GAVTSVETAYDPLVAHLKQLISSVLKLETSKLDTFEPLQSYGLDSFSIMRINQALSEHFS
RLSKTLLYEVESIHDLATTLSQLQPDAVQAWLGAVAPAASQQAPQASARQDAQPRPAVPR
AVDAQAGDAVAIIGINAQFPGAANIEAFWELLRNGVNAVTEIPESRWSLEDFYATDKIEA
IRDGKSYCKQGGFLEQAYDFDEQFFKLSPREILAMDPQERLFMQSCWRALEDSGYTKDKI
KQQYDGDVGVYVGITKTGFNLYGPALWNQDERTIPTTSFSSVASRISYLFDLNGPSMPID
TMCSSSLVAIHEAVHSLKAGRCQMAIVGGVNLYLHPASYVQLCASSMLSQKGQCHSFGDQ
ADGFVPGEGVATLILKPLRQAQADGDRIYATIKGSAVNHGGAAKGYTVPNPKAQTAVIEK
ALNSANITAGELSYIEAHGTGTELGDPIELNALKACFSGNDLPESSCAIGSVKSNIGHLE
AAAGLAGVIKVVLQMQHRVLVPSLHAQTINPNLEFDQSPFYLQRELIEWPSRNNRNRIAG
VSSFGAAGVNAHVILEEYTAPQEQVVGAPVGQEHVQALVFPFSSNTEQGLKRNCRRFLDF
LQAQAPEASTAMDIATFIRATLRGLDNNLSLNQVDDSTPLVDAGLKPFDFYRLFEAVNTR
YGLNLSMLNWQGSVSIGRLVAVIQGGASSSTVPALRDVAFTLQTCRNAHQHRVAICARDL
AGFIERLQRFLGEEDPQVNGSGLYAGVKTHRFEELSKQKALAHDRVQIAFAHHESDALAQ
LWVNGSFEQWEGLYSDGLQPKKCRIPEYAFAANTHSFLDKVGSNARAVRHLDQPSEAGKV
SAEIISHVPVRLEVPAVAGFIRERLAHVLKMDEASINNEVSFVDYGLDSILGVDLIHSLN
EQYRLGLKTTCIYDYPNVEALSRHAHGLITPVTIVDSSTQFARPAPQLLNELPATGQERN
QKPIAIIGMSGRFGGADDTEAFWNNIRDGKDSTESVNRWDLADYLNQEKYRDGVCQRGGF
LNEIDKFDAIFFNISGVEATYMDPQQRLFLEEAWHALEDSGYAGSRLTPEVKDQFGIYVG
GWTGDYNEVFEASEAPAQALWGNMGSMIASRIAYYLDFKGPALTIDTACSSSLVAIHQAC
KDLRLGITNTAIAGGVFVQTTPRLYVQATQAGMLSPTGTCSPFDENADGFVPGEAVGAII
LKRLDDALADGDNIRAVIYGDGINQDGRTNGITAPSAVSQEKLLKRVYKDFGITANDISM
VEAHGTGTNLGDPIEFNALCAAFTTDSAHKNYCALGSVKANIGHTQFAAGISSVIKSVLA
LEHSTIPPLIHHTKGNSRIDLAGSPFYVAKSSQPWQARNGRRLATISAFGASGTNAHVVL
GDLPQPVRHTAEKFGPQLILLSANSDPQLVKLLQKLREHLESDATVSLTNIAYTLACGRR
HFGKRVAILSRSVSELANALGSLLSAAKPSMQIFTPSDLGQGNAQALLKQAHVYIENGQV
NDASFQGSICSLPASPFNSMSFWASSKDKAPAKQASVARPSPPASAPRATATRSKAASKY
CEFTLTVDDFFIADHLVMGQKVLPGVMYIELMKRSVCAVYGDKFKNAYQIALNDIAWVQP
MVFTDATPRLPIIVEVTERGDNADLKVLSRDKKQLYAQAICELSSGQQVLAEDQSFSHLK
AQGIRFDEIDLSAAGLAQYRKVPAAQCYDLLRRHGITHKTRLQGIKALYFSPSTVIAQLQ
LPSILANKQSPFSVHPCLADSALQAISILAVAREKAKQTRDQGGVQTRVPFAIDRFQQYR
EIPLNAWSVGHVLNDGKKEIWTIVIYDAQSNVCAVLDGYRQRILSGVPRLSEA