Protein Info for Psyr_4103 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: cell division-specific peptidoglycan biosynthesis regulator FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 63 to 82 (20 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 125 to 144 (20 residues), see Phobius details amino acids 156 to 173 (18 residues), see Phobius details amino acids 178 to 196 (19 residues), see Phobius details amino acids 203 to 221 (19 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details amino acids 319 to 341 (23 residues), see Phobius details amino acids 355 to 374 (20 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 24 to 379 (356 residues), 432 bits, see alignment E=8.8e-134 PF01098: FTSW_RODA_SPOVE" amino acids 26 to 381 (356 residues), 343.4 bits, see alignment E=7.6e-107

Best Hits

Swiss-Prot: 90% identical to FTSW_PSEFS: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 99% identity to pst:PSPTO_4409)

MetaCyc: 44% identical to peptidoglycan glycosyltransferase FtsW (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZNY9 at UniProt or InterPro

Protein Sequence (404 amino acids)

>Psyr_4103 cell division-specific peptidoglycan biosynthesis regulator FtsW (Pseudomonas syringae pv. syringae B728a ΔmexB)
MIFGVIKPYPSPLISGRGIDLDFPMLVGCLALLGLGLVMITSASSEVAAVQSGNTLYMMT
RHLVYLLIGLGACGVTMMIPVATWQRLGWMMLLGAFGLLLLVLVPGIGREVNGSMRWIGF
GAFNVQPSEIAKVFVVIFLAGYLIRQQQEVRESWMGFFKPFIVLLPMAGLLLMEPDFGAT
VVMMGAAAAMLFLGGVGLFRFSLMVVLAVASVVVLVQAQPYRMARLTNFTDPWADQFGSG
YQLTQALIAFGRGEWFGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGVVGSLITVALFLF
VSIRGMYIGMWAERAKQFFGAYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGG
SSLVICCASLGLLLRIEWESRNNMGSEEAEFKESDFAEETPHGR