Protein Info for Psyr_3652 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Short-chain dehydrogenase/reductase SDR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 PF00106: adh_short" amino acids 15 to 212 (198 residues), 163.6 bits, see alignment E=5.9e-52 PF08659: KR" amino acids 16 to 183 (168 residues), 48.2 bits, see alignment E=1.9e-16 PF13561: adh_short_C2" amino acids 20 to 243 (224 residues), 136.1 bits, see alignment E=2.4e-43

Best Hits

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_3652)

MetaCyc: 53% identical to CAI-1 synthase (Vibrio cholerae O1 biovar El Tor str. N16961)
1.1.1.-

Predicted SEED Role

"Oxidoreductase, short chain dehydrogenase/reductase family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZQ88 at UniProt or InterPro

Protein Sequence (246 amino acids)

>Psyr_3652 Short-chain dehydrogenase/reductase SDR (Pseudomonas syringae pv. syringae B728a ΔmexB)
MFDYSAHPELLKGRIILVTGAARGIGAAAAKAYAAHGATVLLLGRTDASLAQVHDEIKAA
GQLPPLVIPFDLQSADPAQYHALAAMIERTVGRLDGLLHNASIIGPRTSVEHLPGEDFMQ
VMHVNVNATFMLTQALLPLLQRSADASIAFTSSSVGRKGRAQWGAYGVSKFATEGLMQTL
ADELEGVSTVRANSINPGATRTGMRAQAYPDENPQNNPAPEEIMPVYLYLMGPDSKCING
QALNAQ