Protein Info for Psyr_3302 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: mannose-6-phosphate isomerase, type 2 / mannose-1-phosphate guanylyltransferase (GDP)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details TIGR01479: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase" amino acids 4 to 477 (474 residues), 566.6 bits, see alignment E=2.1e-174 PF00483: NTP_transferase" amino acids 6 to 292 (287 residues), 160.1 bits, see alignment E=1.6e-50 PF12804: NTP_transf_3" amino acids 7 to 137 (131 residues), 29.9 bits, see alignment E=1.2e-10 PF01050: MannoseP_isomer" amino acids 323 to 473 (151 residues), 216.2 bits, see alignment E=4.3e-68 PF07883: Cupin_2" amino acids 391 to 456 (66 residues), 32.6 bits, see alignment E=1.1e-11

Best Hits

KEGG orthology group: K00971, mannose-1-phosphate guanylyltransferase [EC: 2.7.7.22] (inferred from 100% identity to psb:Psyr_3302)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.22

Use Curated BLAST to search for 2.7.7.22

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZR88 at UniProt or InterPro

Protein Sequence (485 amino acids)

>Psyr_3302 mannose-6-phosphate isomerase, type 2 / mannose-1-phosphate guanylyltransferase (GDP) (Pseudomonas syringae pv. syringae B728a ΔmexB)
MSTLIPCIIAGGSGTRLWPVSREAMPKPFMRLPDGQSLLQKTFLRAVGLPGVERLLTVTN
REVYFRTVDDYRQLNKGNARLDFILEPFGRNTAAAVAAAALHVSQLYGDEAQLLVLPADH
LITDVAEFSRAVTAAQKLAAEGWLVTFGILPTAPETGFGYIEKGPVLNADACQVARFVEK
PDAITAQGYLDSGQHFWNAGMFCMRADAVLRELRKHAPDVLSAVSACLESSPRKEGNREL
QVELDSESFALTPDISIDYALMERSEKVAVVPCQLGWSDIGSWQAVRELSPVDAQGNYCN
GETVLHDVSNCYIDSPKRLVGAIGLDNLIIIDTPDALLIADGGRSQDVRIIAQELKRQGH
DAYRLHRTVTRPWGTYTVLEEGKRFKIKRIVVRPQASLSLQMHHHRSEHWIVVSGMARVT
NGEREFMLDTNESTFIKPGHTHRLVNPGVIDLVMIEVQSGEYLGEDDIVRFTDIYGRVPD
KAMKS