Protein Info for Psyr_3219 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Peptidase M24

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 PF01321: Creatinase_N" amino acids 14 to 136 (123 residues), 45.1 bits, see alignment E=2.8e-15 PF16189: Creatinase_N_2" amino acids 156 to 313 (158 residues), 149.2 bits, see alignment E=2.3e-47 PF00557: Peptidase_M24" amino acids 317 to 531 (215 residues), 164.2 bits, see alignment E=7.1e-52 PF16188: Peptidase_M24_C" amino acids 542 to 601 (60 residues), 80.5 bits, see alignment 1.4e-26

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 100% identity to psb:Psyr_3219)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZRH1 at UniProt or InterPro

Protein Sequence (602 amino acids)

>Psyr_3219 Peptidase M24 (Pseudomonas syringae pv. syringae B728a ΔmexB)
MSTQSNASSDVAERLAQTRALMSRERIDAYLVPSADPHLSEYLPGYWQGRQWLSGFHGSV
GTLIITQDFAGIWADSRYWEQATKELAGSGIELVKLVPGQQGPLEWLADEAKAESVVAVD
GAVLAVASSRTLASKLYERGARLRTDIDLLTELWQDRPALPSHPIYEHLPPQASLDRSAK
LARVRQIIAERKADWHFIATLDDIAWLFNLRGADVSYNPVFIAFALIGPQSVTLFVDSKK
VPDPVRARLERDGINLMEYTQIGAALRELPKDARLLVDPARVTCGLLDYLDSEVTLVEGL
NPSTLLKSQKTEADTAHIRQAMEQDGAALCEFFAWLDSALGREPVSELTIDEKLTQARER
RPGYVSPSFATIAGFNANGAMPHYRATEAEHARIEGDGLLLIDSGGQYLGGTTDITRMVA
IGTPSAEQKQDCTRVLKGVIALSRAHFPKGILSPLLDAIARAPIWSEGVNYGHGTGHGVG
YFLNVHEGPQVIAYQAPATPQTAMLPGMITSIEPGTYRPGRWGVRIENLVINQEAGKTEF
GEFLRFETLTLCPIDTRCLEVSMLNAEERAWLNDYHVQVLKRLSPLLQGTALLWLQARTI
PV