Protein Info for Psyr_2754 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: regulatory protein, TetR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 PF00440: TetR_N" amino acids 36 to 78 (43 residues), 40 bits, see alignment 2.7e-14 PF16925: TetR_C_13" amino acids 104 to 216 (113 residues), 155.2 bits, see alignment E=6.4e-50

Best Hits

Swiss-Prot: 52% identical to ACUR_RHOS4: Transcriptional regulator AcuR (acuR) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_2754)

Predicted SEED Role

"transcriptional regulator, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZSS9 at UniProt or InterPro

Protein Sequence (219 amino acids)

>Psyr_2754 regulatory protein, TetR (Pseudomonas syringae pv. syringae B728a ΔmexB)
MTQPTTSLPTPSLARPRRPGRPPKVDRDNLETREALLRRGLEVLTEQSFSATGLDYILKE
VGIPKGSFYHYFPSKEAFGRAVLDEYARYFAQRLDRWLLDEALSPLERLVGFVQSAKGGM
ARHDYRRGCMVGNLGQEISLLPDGFREALEQTLLDWQSKLAGCLRAAQSMGELAADADCD
ELAAFFWIGWEGAVLRARLVKSATPLNTFIAGYLRGLPQ