Protein Info for Psyr_2493 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 407 transmembrane" amino acids 21 to 50 (30 residues), see Phobius details amino acids 59 to 77 (19 residues), see Phobius details amino acids 95 to 115 (21 residues), see Phobius details amino acids 123 to 149 (27 residues), see Phobius details amino acids 161 to 180 (20 residues), see Phobius details amino acids 186 to 206 (21 residues), see Phobius details amino acids 229 to 255 (27 residues), see Phobius details amino acids 261 to 280 (20 residues), see Phobius details amino acids 289 to 309 (21 residues), see Phobius details amino acids 315 to 336 (22 residues), see Phobius details amino acids 351 to 374 (24 residues), see Phobius details amino acids 380 to 399 (20 residues), see Phobius details PF07690: MFS_1" amino acids 32 to 312 (281 residues), 72.7 bits, see alignment E=1.4e-24

Best Hits

Swiss-Prot: 52% identical to Y3873_PSEAB: Uncharacterized MFS-type transporter PA14_38730 (PA14_38730) from Pseudomonas aeruginosa (strain UCBPP-PA14)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_2493)

Predicted SEED Role

"transporter, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZTJ0 at UniProt or InterPro

Protein Sequence (407 amino acids)

>Psyr_2493 Major facilitator superfamily (Pseudomonas syringae pv. syringae B728a ΔmexB)
MMRHSHRPPAKSPMPAAHPGSMTITLQIVSIVFYTFIAFLCIGLPIAVLPGYVHDQLGFS
PLIAGLTIASQYLATLLSRPFAGRATDTLGSKRSIVFGLWGIVISGSMTLLATLLHEFAT
LSLSILIVARLFLGVSQGLIGVGTINWCIGKVGTEHTARSISWNGIASYGAIAIGAPLGV
VVIDSIGFNSLGIALMVMAGLALRLIRDKPSVPIIVGERLPYWSVFGRIAPYGLGLTLSS
IGYGTLTTFITLFYLNRGWEGAAYCLSMFGVCFILARLLFIGAINRLGGYNAAIVCMAVE
ICGLLMLWLSPSSSVALAGAGLTGVGLSLVYPALGVEAIKCVPTPSRGAGLSAYAVFFDL
ALAIAGPVMGAIALGQGYDWIFFYAALLSVCALALTIWLSRRATQLG