Protein Info for Psyr_1971 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: Peptidase S45, penicillin amidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 779 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF01804: Penicil_amidase" amino acids 36 to 764 (729 residues), 468.8 bits, see alignment E=2.4e-144

Best Hits

Swiss-Prot: 100% identical to PVDQ_PSEU2: Acyl-homoserine lactone acylase PvdQ (pvdQ) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: K07116, (no description) (inferred from 100% identity to psb:Psyr_1971)

Predicted SEED Role

"Acyl-homoserine lactone acylase PvdQ (EC 3.5.1.-), quorum-quenching" in subsystem Siderophore Pyoverdine (EC 3.5.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.-

Use Curated BLAST to search for 3.5.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZV08 at UniProt or InterPro

Protein Sequence (779 amino acids)

>Psyr_1971 Peptidase S45, penicillin amidase (Pseudomonas syringae pv. syringae B728a ΔmexB)
MIISRPLCSFVFAGLSFAVILPAQALVEPGNQAARAEIRRTGFGVPHIVAANERGLGYGI
GYAYAQDNLCLLANEVVTVNGQRSRYFGPDKATLEQRNNMASDLLFQWLNTPQALADFWN
AQPREIRQLMQGYVAGYNRSLAEQTTQGLPQPCAAEWVRPISTDDLLRLTRRLLVEGGVG
QFAEALAGATPPAQQKPLQVDAQQAQALQLAAARNQRFALERGSNAVAIGRELSANGRGM
LLANPHFPWGGGMRFYQMHLTIPGKLDVMGAALPGLPLINIGFNQHLAWSHTVDTSKHFT
LHRLQLDPKDSTRYLLDGQSVAMGKQQVSVDVKQADGSLKSVPRIVYSSIFGPVVQWPGK
LDWDSKFAFSLRDANLQNDRVLQQWYAMDKADSLKAFQDSVRKIQGIPWVNTLAVDAQGQ
ALYMNLSVVPNVDAARLARCSDPRIGTELIVLDGSRSECNWEVSAEAAQAGIYPSSRQPQ
LLRTDFVQHSNDSAWMVNPAAPLQGFSPLISQDGQPLGQRARFALDRLESLKTAGKISVE
NLQAMVMDNEVYQAGQVLPDLLTFCASELGDDAARLAPLCAALKDWDGRADLNSGIGFVY
FQKIMTSMQAVASRWRVAFDPQDPVHTPSGLAIENPSVATALRAAMLAAVDDVAKAGLPA
GSKWGDIQVSSISGKQIPIHGGPAGLGVYNAMQTVAGKDGKREVVSGTSYLQVVTFDEQG
PKAQGLLAFSESSNPQSAHSSDQTEAFSKKQWQALPFTEQQIKADPAYEVQVISEEPDR