Protein Info for Psyr_1273 in Pseudomonas syringae pv. syringae B728a ΔmexB

Annotation: NUDIX hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 transmembrane" amino acids 167 to 183 (17 residues), see Phobius details PF00293: NUDIX" amino acids 26 to 113 (88 residues), 47.5 bits, see alignment E=9.3e-17

Best Hits

Swiss-Prot: 43% identical to NUDL_SALPK: Uncharacterized Nudix hydrolase NudL (nudL) from Salmonella paratyphi A (strain AKU_12601)

KEGG orthology group: None (inferred from 100% identity to psb:Psyr_1273)

Predicted SEED Role

"Hypothetical nudix hydrolase YeaB" in subsystem Nudix proteins (nucleoside triphosphate hydrolases)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q4ZWZ8 at UniProt or InterPro

Protein Sequence (198 amino acids)

>Psyr_1273 NUDIX hydrolase (Pseudomonas syringae pv. syringae B728a ΔmexB)
MLDELLRRVVRHTPETLDSDRQFPEAAVLVPITRSEQPELILTLRASGLSTHGGEVAFPG
GRRDPGDPDLIFTALREAEEEIGLPPGLVEVIGPLSPLISKHGIKVTPYVGVIPDFVEYQ
PNDAEIAAVFSVPLEFFRQDTREHTHRIDYEGRSWYVPSYRYGEYKIWGLTAIMIVELVN
VLYDTRISLHHPPERSTI