Protein Info for Psyr_1096 in Pseudomonas syringae pv. syringae B728a ΔmexB
Annotation: glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 90% identical to GCSP1_PSEPF: Glycine dehydrogenase (decarboxylating) 1 (gcvP1) from Pseudomonas fluorescens (strain Pf0-1)
KEGG orthology group: K00281, glycine dehydrogenase [EC: 1.4.4.2] (inferred from 64% identity to adk:Alide2_2543)MetaCyc: 59% identical to glycine cleavage system P protein (Chlamydomonas reinhardtii)
Predicted SEED Role
"Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2)" in subsystem Glycine and Serine Utilization or Glycine cleavage system or Photorespiration (oxidative C2 cycle) (EC 1.4.4.2)
MetaCyc Pathways
- glycine biosynthesis II (3/3 steps found)
- glycine cleavage (3/3 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.4.4.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q4ZXH2 at UniProt or InterPro
Protein Sequence (954 amino acids)
>Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit (Pseudomonas syringae pv. syringae B728a ΔmexB) MTDRIELTTANEFIARHIGPRAADELAMLQTLGFDSIEALSESVIPESIKGTSVLNLPAG QSEADALASIKAIASKNQLFKTYIGQGYYNTHTPAPILRNLLENPAWYTAYTPYQPEISQ GRLESLLNFQTLISDLTGLPIANASLLDEATAAAEAMTFCKRLSKNKASQQFFASSHCHP QTLDVLRTRAEPLGITVVVADEHELGDVSDYFGALLQYPASNGDVFDYRELVERFHAANA LVAVAADLLALTLLTPPGEFGADVAIGSAQRFGVPLGFGGPHAAYFSTRDAFKRDMPGRL VGVSVDRHGKQALRLAMQTREQHIRREKATSNICTAQVLLANIASMYAVYHGPRGLTQIA NRVHQLTAILAEGLSTLGLNAEQAFFFDSLTLHTGDRTAALHAAARARHINLREIDDQRL GLSLDETTSQSAVETLWAIFANDGQSLPDFAALADSVQSRLPAGLLRQSAILSHPVFNRY HSETELMRYLRKLADKDLALDRTMIPLGSCTMKLNAASEMIPVTWAEFGNLHPFAPAEQS AGYQQLTDELEAMLCAATGYDAISLQPNAGSQGEYAGLLAIRAYHQSRGDEHRDICLIPS SAHGTNPATANMAGMRVVVTACDARGNVDIEDLRAKAVQHRDQLAAIMITYPSTHGVFEE GIREICGIVHDNGGQVYIDGANMNAMVGLCAPGKFGGDVSHLNLHKTFCIPHGGGGPGVG PIGVKSHLAPFMPGHARMERKEGAVCAAPFGSASILPITWMYIRMMGGEGLKRASQLAIL NANYISRRLEEHYPVLYTGSNGLVAHECILDLRPIKDSSGISVDDVAKRLIDFGFHAPTM SFPVAGTLMIEPTESESREELDRFCDAMIKIREEIRAVENGTLDKDDNPLKNAPHTAAEI VGQWSHPYSREQAVYPVDSLIENKYWPPVGRVDNVFGDRNLVCACPSIENYQEA