Protein Info for PfGW456L13_948 in Pseudomonas fluorescens GW456-L13

Annotation: Ribose 5-phosphate isomerase A (EC 5.3.1.6)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 224 TIGR00021: ribose 5-phosphate isomerase A" amino acids 7 to 219 (213 residues), 208.5 bits, see alignment E=4e-66 PF06026: Rib_5-P_isom_A" amino acids 53 to 217 (165 residues), 202 bits, see alignment E=2.9e-64

Best Hits

Swiss-Prot: 96% identical to RPIA_PSEFS: Ribose-5-phosphate isomerase A (rpiA) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K01807, ribose 5-phosphate isomerase A [EC: 5.3.1.6] (inferred from 96% identity to psp:PSPPH_4880)

MetaCyc: 63% identical to ribose-5-phosphate isomerase A (Escherichia coli K-12 substr. MG1655)
Ribose-5-phosphate isomerase. [EC: 5.3.1.6]

Predicted SEED Role

"Ribose 5-phosphate isomerase A (EC 5.3.1.6)" in subsystem Calvin-Benson cycle or D-ribose utilization or Pentose phosphate pathway (EC 5.3.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0F4TVE7 at UniProt or InterPro

Protein Sequence (224 amino acids)

>PfGW456L13_948 Ribose 5-phosphate isomerase A (EC 5.3.1.6) (Pseudomonas fluorescens GW456-L13)
MNQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAKHKGAFDGAVASSEAT
AARLKGHGIPVYELNTVSDLEFYVDGADESDEHLNLIKGGGAALTREKIVAAVAKTFICI
ADASKLVPVLGTFPLPVEVIPMARSHVARELVKLGGDPVYREGVLTDNGNIILDVFNMQI
TNPVELETQINAIVGVVTNGLFAARPADLLLLGTSEGVKTLRAE