Protein Info for PfGW456L13_59 in Pseudomonas fluorescens GW456-L13

Annotation: Sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 916 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details transmembrane" amino acids 163 to 181 (19 residues), see Phobius details amino acids 192 to 213 (22 residues), see Phobius details amino acids 227 to 246 (20 residues), see Phobius details amino acids 258 to 276 (19 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details amino acids 312 to 336 (25 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details PF07696: 7TMR-DISMED2" amino acids 20 to 150 (131 residues), 71.7 bits, see alignment E=1.5e-23 PF07695: 7TMR-DISM_7TM" amino acids 162 to 364 (203 residues), 82 bits, see alignment E=1.5e-26 PF00512: HisKA" amino acids 388 to 453 (66 residues), 73.1 bits, see alignment 3.9e-24 PF02518: HATPase_c" amino acids 500 to 614 (115 residues), 59.2 bits, see alignment E=1.3e-19 PF00072: Response_reg" amino acids 634 to 750 (117 residues), 70.1 bits, see alignment E=4.6e-23 amino acids 784 to 898 (115 residues), 79.6 bits, see alignment E=4.9e-26

Best Hits

KEGG orthology group: None (inferred from 88% identity to pfo:Pfl01_0611)

Predicted SEED Role

"Sensor histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QIC9 at UniProt or InterPro

Protein Sequence (916 amino acids)

>PfGW456L13_59 Sensor histidine kinase/response regulator (Pseudomonas fluorescens GW456-L13)
LTVTLLTLLCMLPAQAAQGSGWAVLLDEQGDLQLSDIRSARYTNQFSPIELDHITAAEPD
GALWLRFRLAPGKHEQLLRVFAPDLRQFNMYVLDGDKLIDQSSTGNEHPQSERPLPSSDF
MLALPQSDTPLDVYLRLASDHQLRPYITLQSAINSAANQNQTLIYGLLFGCIAMLILHNL
IRYAYTRSHSALWLATCEGLLMLSLLLLLNLAGPWLPDWHALQTPGAYLALLMTAPCGLM
LAYRFFAPLGPHPLNRLLLGEVVLITACSLMLLFVNTLPLNFITYGLVALAGLTMLFISA
YHWQKGYRPARLFVAAMAVFNLGTLVILPALLGLTLIEPHGLITTLLAFICISGLLMSIA
LSERQRRITEDRFSISRDLAASNAEINAKAEFLAKISHEIRTPMNGVLGMTELLLGTPLS
VKQRDYVQTIHSAGNELLTLINEILDISKLESGQIELDDVQFDLNALIEDCLSIFRAKAE
QQNVELISFIQPQVPRVISGDPTRLRQTLLSLLENALKKTDEGEILIVVALDERNTKPRL
RIAVQDSGEPMDAEERDALMHAELHSRHFLSATQLGGNLGLVIARQLIRLMQGEFGIKSG
NNQGSTLWLTLPLDPDRLEHPTSDLDGPLQGARVLVVDDNDTCRKVLVQQCSAWGLNVSA
ASSGKEALALLRTKAHLRDYFDIVLLDQNMPGMTGMQLAAKIKEDPSLNHDILLIMLTGI
SNAPSKIIARNSGIKRILAKPVAGYTLKTTLADELTQRNKGLVATQPVPIGPTLPVKVPC
DFRILVAEDNSISTKVIRGMLSKLNLQPDTACNGEEALQAMKAQRYDLVLMDCEMPILDG
FSATQQLRAWEVGNQRVRTPVVALTAHILAEHKERARQAGMDGHMAKPVELSQLRELIEH
WVAQRDQQKRTTTPTS