Protein Info for PfGW456L13_588 in Pseudomonas fluorescens GW456-L13

Annotation: GGDEF domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 652 PF20975: DGCcoil" amino acids 4 to 474 (471 residues), 240.9 bits, see alignment E=2.4e-75 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 490 to 650 (161 residues), 168.7 bits, see alignment E=4.6e-54 PF00990: GGDEF" amino acids 492 to 648 (157 residues), 156.3 bits, see alignment E=5.8e-50

Best Hits

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QET9 at UniProt or InterPro

Protein Sequence (652 amino acids)

>PfGW456L13_588 GGDEF domain protein (Pseudomonas fluorescens GW456-L13)
MSDEAQRWKEKYLKSIEQQEKLERRWDARLDLLRRGLVRSTLAAEGTDRAVDQCMKEMRE
VVRTDDMDAGLAALIPRLEKAVLDSEQRRETRVNQTSAALTALVTQLQTLPLPRDVSRPL
KNFAKHLDARVSQAREMPLLLSELSGLQGKALSQLETPTENGRPGLLQRLFGGREAQETE
ASTAAAPALAAPVAESPAASCEVPAVERVEDEFAPTEPTVAFAPPAAEPQPPSAAAAEIE
SAEKPTPETIATSPESQANPDELTAQASPDSLPLPPIPMQDVAVVDQASSEHDILYALPD
SPEPSYSSVASHIEDTLLGLLDDLTLPERHRPQAESMRDRLKNGLNWYELLPILDDFATL
MLAITDSGQHEFEAYLQRLNERLESFQSNLQAATAGHADNRSAARQMDTQIREQVDGLQS
SMQEAADLEDLKHVLENHLEGLLGTMDQHQKQRDEREQEVAARLHSLAERVAHMEQEAQG
YREHLEEQRQKALVDPLTGLPNRAAWSERLGHEVTQWQQHGNTLLLAMLDLDHFKRINDN
YGHLAGDKVLKIIASVLRKRLRGTDFIARFGGEEFVLLMPSTVPAAGLKMLESLRASIEA
CPFHFKGEPVTITVSIGMTAFRPGEHSDQVLKRADQALYRAKNAGRNRVEPS