Protein Info for PfGW456L13_535 in Pseudomonas fluorescens GW456-L13

Annotation: Type I secretion system, outer membrane component LapE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 31 to 439 (409 residues), 280 bits, see alignment E=1.8e-87 PF02321: OEP" amino acids 36 to 228 (193 residues), 96.7 bits, see alignment E=7.7e-32 amino acids 248 to 432 (185 residues), 94.9 bits, see alignment E=2.7e-31

Best Hits

KEGG orthology group: K12543, outer membrane protein LapE (inferred from 94% identity to pfo:Pfl01_0134)

Predicted SEED Role

"Type I secretion system, outer membrane component LapE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QH24 at UniProt or InterPro

Protein Sequence (462 amino acids)

>PfGW456L13_535 Type I secretion system, outer membrane component LapE (Pseudomonas fluorescens GW456-L13)
VIQDKKFWEIPTMRSPLFMAIPFVLAASFVQAQSLPEAMQQALDVHPEVQAGVNSRLAAD
YQLKAAKGGYLPRVDLLGGYGREGTDSVTTRTDGSNNHWQTLNRSESNLRLTQMVFDGFA
TSSEVGRQQATVNSRAYSLLSTSERTGLTVAQVYLDVLTRREFVRLAEDNLKSHQRIYDQ
IQLRTQRGVGSGADLDQAEARMAQARNNLITEQTNLADAETNYLSAVGQMPDQLERPASF
MALMPANLNEARAQMLENSPILRSAESDIAAAEKQYDTAKSTFYPRFDAELGRSADNDID
GQNGHNNEWQAMLRMRFNLYAGGSNKADLESKSYLSNQALDIRNNALRQLNEELGLAWNA
LNNANAQVPIAQQYVDHSTAVRTAYQRQFSLGERTLLDLLDSENELFSSSRRLAEIKNIQ
LFTQYRIKATMGELLKSQGVVAPLASVVQNDMKPKVQLPGMN