Protein Info for PfGW456L13_507 in Pseudomonas fluorescens GW456-L13

Annotation: Inner membrane component of tripartite multidrug resistance system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 683 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 32 to 48 (17 residues), see Phobius details amino acids 55 to 74 (20 residues), see Phobius details amino acids 80 to 99 (20 residues), see Phobius details amino acids 106 to 125 (20 residues), see Phobius details amino acids 140 to 156 (17 residues), see Phobius details amino acids 358 to 379 (22 residues), see Phobius details amino acids 385 to 402 (18 residues), see Phobius details amino acids 412 to 431 (20 residues), see Phobius details amino acids 437 to 455 (19 residues), see Phobius details amino acids 461 to 481 (21 residues), see Phobius details amino acids 493 to 513 (21 residues), see Phobius details PF04632: FUSC" amino acids 6 to 661 (656 residues), 547.2 bits, see alignment E=7e-168 PF13515: FUSC_2" amino acids 19 to 150 (132 residues), 65.1 bits, see alignment E=7.1e-22

Best Hits

KEGG orthology group: None (inferred from 87% identity to pfo:Pfl01_0171)

Predicted SEED Role

"Inner membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QJT0 at UniProt or InterPro

Protein Sequence (683 amino acids)

>PfGW456L13_507 Inner membrane component of tripartite multidrug resistance system (Pseudomonas fluorescens GW456-L13)
MPPARDWFYGVRTFAASMIALYIALLMQMPRPYWAMATVYIVSSPFLGPTSSKALYRAVG
TFIGAAAAVLFVPMFVQSPYVLVVVIALWTGTLLFLSLHLRTANNYALMLAGYTLPLIAL
PVVNNPLGVWDVAEARTEEIFLGIAVAAVVGAMFWPRRLAPVFNDSVSKWFTDASTYSLR
FLSRNVQPEEVSALRASMVATFNSLELMIGQLPHEGSRPQTVRNTKELRGRMIHLLPVID
ALDDALYALERRTPELVDKFAPLLTATTEWLEHKDADLARWQALKDKLEALQPAPEALDD
RKQLLFSNAIYRLGEWIDLWQDCRSLQYAIQCESQDNWRAVYRHWRLGRLSPFLDRGLMF
YSAASTVTAIIVASVLWILLGWTDGGSAVILAAVACSFFASMDDPAPQIYRFFFWTAMSV
VFASLYLFLVLPNLHDFPMLVLAFAVPFICVGTLTVKPQFYLGMLLTLVNTSSFISIQGA
YDADFLSFANSNLAGPMGLLFAFIWTLIARPFGAELAAKRLTRFSWRDIVGLSEPATLSE
HRLLGIRMLDRLMQHLPRLAMTGQDSGVALREVRVALNLLDLLAYTPRVLGVPQVLLRQV
VAEVGEYFKACLKAGERLQAPSPLLMTLDRTRRALSGAGDDETRRHLLHALSGLRLALLP
GVEFVGSAEPEEPLPHGIDGAPL